Elena Buglo, PhD: Exploring Genetic Diversity, Neurodiversity, and the Power of Unique Physiology

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In this captivating episode, I'm joined by Elena Buglo. Elena's background is a PhD in neurogenetics from the University of Miami Miller School of Medicine. She now works supporting a rare disease biotech company in medical affairs, and she leads with great passion for neuroscience, genetics and genetic editing technologies. In her research work she utilized CRISPR technology to model and study various rare disease genes. She recently started her podcast on gene therapies and precision medicines. Check it out and support her by subscribing and giving a 5-star review at : https://podcasters.spotify.com/pod/show/gene-therapy-insights

Elena discusses the significance of genetic diversity, advocating for a personalized approach to health that celebrates our unique genetic makeup. She explores neurodiversity, challenging conventional views on cognitive and physiological differences, and emphasizes the holistic interconnectedness of our biological systems. Her expertise illuminates the critical role of mitochondria and other cellular components in overall health, highlighting the need for comprehensive health strategies.

This episode is a must-listen for those interested in genetic science, personalized medicine, and the future of healthcare. Elena's perspectives encourage a deeper understanding of our biological uniqueness and the potential of gene editing technologies to revolutionize health and wellness. Whether you're in the medical field, facing genetic health challenges, or simply fascinated by science, Elena's insights offer valuable guidance on navigating the complexities of human biology and the promise of tailored healthcare solutions.
Key Points From This Episode:

Sleep and Overall Health [00:01:53]
Introduction to Neurogenetics Discussion [00:03:53]
Explaining Neurogenetics in Simple Terms [00:05:0]
The Impact of Debilitating Genetic Diseases [00:07:13]
Genetics vs. Epigenetics [00:09:01]
Personal Genetic Insights and Lifestyle Adjustments [00:14:05]
The Complexity of Genetic Influence on Health [00:27:10]
The Risks of Over-Optimizing Health [00:29:57]
The Role of Geneticists in Healthcare [00:37:45]
Genetic Testing and Personalized Medicine [00:42:50]
BDNF Levels and Genetic Variability [00:44:46]
Genetic Compensation and Physiological Adaptation [00:47:59]
Analogy for Genetic Function and Adaptation [00:53:52]
The benefits of gene editing [00:56:35]
Neurodiversity and unique phenotypes. [01:03:17]
Living with ADD and medication [01:05:39]
Genetic dating app. [01:11:40]
Reproduction and genetic optimization. [01:13:23]
Attraction to different genetic backgrounds. [01:18:23]
Genetic attraction and relationships. [01:22:37]
Lysosomal storage disorders. [01:29:57]
Unique backgrounds and accepting differences. [01:33:17]
Genetics and intuition. [01:39:05]
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Links Mentioned in Today’s Episode:
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People

• Elena Buglo
  • Linkedin
• George Church:
  • Wiki
  • Twitter: @geochurch
• Ben Greenfield:

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챕터

1. Trailer (00:00:00)

2. Magnesium Supplement (00:00:26)

3. CRISPR gene editing (00:04:14)

4. Epigenome editing (00:10:59)

5. Genetic plasticity and adaptation (00:13:11)

6. DNA and debilitating diseases (00:18:05)

7. Partially expressed genetic disorders (00:23:00)

8. Glucose deprivation and stress (00:28:16)

9. Less is more (00:33:10)

10. Genetic origins of cerebral palsy (00:38:27)

11. Genetic test and BDNF levels (00:43:19)

12. Genetic diseases and natural history (00:46:10)

13. Gene expression and BDNF factor (00:49:37)

14. Water pressure analogy (00:54:01)

15. The benefits of gene editing (00:56:35)

16. eurodiversity and unique phenotypes (01:03:17)

17. Living with ADD and medication (01:05:39)

18. Genetic dating app (01:11:40)

19. Reproduction and genetic optimization (01:13:23)

20. Attraction to different genetic backgrounds (01:18:23)

21. Genetic attraction and relationships (01:22:37)

22. Lysosomal storage disorders (01:29:57)

23. Unique backgrounds and accepting differences (01:33:17)

24. Genetics and intuition (01:39:05)