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The Link Between Proteins Alzheimer’s and Parkinson’s Diseases
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Manage episode 446209115 series 3046722
UCTV에서 제공하는 콘텐츠입니다. 에피소드, 그래픽, 팟캐스트 설명을 포함한 모든 팟캐스트 콘텐츠는 UCTV 또는 해당 팟캐스트 플랫폼 파트너가 직접 업로드하고 제공합니다. 누군가가 귀하의 허락 없이 귀하의 저작물을 사용하고 있다고 생각되는 경우 여기에 설명된 절차를 따르실 수 있습니다 https://ko.player.fm/legal.
Proteins are large biomolecules that play critical roles in a host of cellular processes, from cell signaling to regulating the immune system. However, these life-giving proteins can form toxic aggregate species that have been linked to several neurodegenerative diseases, including Alzheimer’s Disease and Parkinson’s Disease. In this program, UC Santa Barbara professor Joan-Emma Shea discusses the tau protein as a model system to study neurodegeneration. Shea says this protein plays a functional role in stabilizing microtubules in brain cells, but it can also self-assemble to form amyloid fibrils (large “clumps” of Tau proteins). There are several neurodegenerative diseases linked to tau assembly, including Alzheimer’s Disease, Pick’s Disease, and chronic traumatic encephalopathy, and they are collectively known as tauopathies. Shea discusses new insights into tauopathies and targets for therapeutics. Series: "GRIT Talks" [Science] [Show ID: 40083]
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