What the heck is mTOR?

The Lab Report

There are a lot of terms bantered about in the biohacker and longevity space. With that, you’ve likely heard of mTOR – mechanistic (mammalian) target of rapamycin. But what exactly is it? mTOR is a key regulator in your body’s metabolic and growth processes. It integrates various signals, including nutrients and growth factors, to control processes like protein synthesis, autophagy, and lipid metabolism. Because it regulates growth, dysregulation of mTOR has been implicated in various diseases, including cancer.

In today’s episode, we simplify the science behind mTOR – mechanistic target of rapamycin. This crucial enzyme may be the key to unlocking groundbreaking advancements in wellness, anti-aging, disease prevention, and health optimization.

Today on The Lab Report:

• 3:00 mTOR – Why are we even covering this topic?
• 4:40 What is it? Muscle growth vs. autophagy
• 6:25 Why is it called mTOR?
• 9:00 Highly conserved and in every cell, every organ
• 10:30 mTORC1 and mTORC2
• 11:25 Influences and sensors – it’s more than leucine
• 14:25 Dysregulation of mTOR – does protein cause cancer?
• 17:30 Should people take rapamycin for longevity?
• 20:20 Question of the Day
  • Where does mTOR work in muscle protein synthesis?

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