Why Chronic Stress Is Breaking Down Every System in the Body

The Trusted Pharmacist

In short bursts, stress is protective. But what happens when your body’s “temporary survival mode” becomes your default state?

That’s where so many of us live today, locked in fight-or-flight 24/7. Our hearts race, our sleep suffers, our moods swing, and we can’t seem to calm down even when nothing’s wrong. What once gave us an edge now keeps us wired and depleted.

And when stress stops being occasional and becomes constant, it stops protecting you and starts dismantling your health.

Chronic stress reshapes your cortisol curve, depletes essential nutrients, wrecks your thyroid, gut, and hormones, and sets the stage for premature aging and disease. It doesn’t just make you “stressed out”, it rewires every system in your body to run on empty.

How does stress wreck every aspect of your health? How do we get our cortisol back under control?

In this episode, I unpack why our modern stress load is unlike anything our ancestors faced, and how it’s hurting us.

You’ll learn how to spot the warning signs, where stress is silently sabotaging your health, and how to build back your resilience.

Things You’ll Learn In This Episode

-Stress, the nutrient vampire

Cortisol doesn’t just rev you up; it drains your reserves. Which vitamins and minerals disappear first under pressure, and why does that accelerate aging and inflammation?

-How stress hijacks hormones & immunity Long-term cortisol dominance steals building blocks from sex hormones, shuts down thyroid function, and even drives infertility and autoimmune disease. Why does your body do this on purpose, and how can you reverse it?

-A framework to heal your adrenals What’s the realistic timeline to rebuild healthy adrenals, and which steps matter most when you’re already burned out?

PS. If you enjoy the show, remember to leave a review on your favorite podcast app! Reviews help the podcast reach a wider audience and help more people.

About Your Host

Steve Hoffart is an award-winning pharmacist, entrepreneur, speaker, and podcaster. As the visionary founder of Magnolia Pharmacy, Steve saw a need for a more personal pharmacy that could make a bigger impact. Today, Steve and his team of experts deliver on that promise, working with patients and their physicians to solve medication problems and offer personalized solutions to achieve better health and wellness. As host of The Trusted Pharmacist podcast and through his combined reach of over 250,000 on social media, Steve shares actionable advice on nutrition, supplements, and wellness strategies while advocating for meaningful change in healthcare.

Follow the Trusted Pharmacist on Apple Podcasts, Spotify, or your favorite podcast app so you get the latest episodes! If the show has been helpful, leave us a review on Apple Podcasts —or simply tell a friend about the show. Each time you share the show, you are potentially changing someone’s life!