Episode 53 - Alzheimer's Drug Was it Approved or Not: I Can't Remember

Breaking Bad Science

Daniel에서 제공하는 콘텐츠입니다. 에피소드, 그래픽, 팟캐스트 설명을 포함한 모든 팟캐스트 콘텐츠는 Daniel 또는 해당 팟캐스트 플랫폼 파트너가 직접 업로드하고 제공합니다. 누군가가 귀하의 허락 없이 귀하의 저작물을 사용하고 있다고 생각되는 경우 여기에 설명된 절차를 따르실 수 있습니다 https://ko.player.fm/legal.

4y ago 31:49

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There are few things more terrifying than considering the possibility of developing Alzheimer's towards the end of one's life. With modern medicine the way it is there could be little doubt we've made great advances in the treatment of this disease. So it might surprise you to hear that the recent Biogen news means that the FDA has approved the first drug for the treatment of Alzheimer’s in twenty years. Turns out, though, that's not actually what makes it such big news. Join hosts Shanti and Danny as we talk about what’s going on with aducanumab, Biogen, and some strange moves by the FDA.

References

Lovelace, B.; Third Member of the Prestigious FDA Panel Resigns Over Approval of Biogen’s Alzheimer’s Drug. CNBC. 10-Jun-2021. https://www.cnbc.com/2021/06/10/third-member-of-prestigious-fda-panel-resigns-over-approval-of-biogens-alzheimers-drug.html
Knopman, D., et. al.; Failure to Demonstrate Efficacy of Aducanumab: An Analysis of the EMERGE and ENGAGE Trials as Reported by Biogen, December 2019. Alzheimer’s & Dementia. 10-Nov-2020. 17:4 (696 - 701). Doi: https://doi.org/10.1002/alz.12213
Shankar, G., et. al.; Amyloid B-Protein Dimers Isolated Directly from Alzheimer Brains Impair Synaptic Plasticity and Memory. Nature Medicine. 22-Jun-2008. 14:8 (837 - 842). Doi: https://doi.org/10.1038/nm1782

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