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Olivia Grant에서 제공하는 콘텐츠입니다. 에피소드, 그래픽, 팟캐스트 설명을 포함한 모든 팟캐스트 콘텐츠는 Olivia Grant 또는 해당 팟캐스트 플랫폼 파트너가 직접 업로드하고 제공합니다. 누군가가 귀하의 허락 없이 귀하의 저작물을 사용하고 있다고 생각되는 경우 여기에 설명된 절차를 따르실 수 있습니다 https://ko.player.fm/legal.
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The Role of Mitochondrial Quality Control Pathways in Familial and Non-Familial Variants of Disease, with David Tumbarello

1:09:29
 
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Manage episode 288180034 series 2859702
Olivia Grant에서 제공하는 콘텐츠입니다. 에피소드, 그래픽, 팟캐스트 설명을 포함한 모든 팟캐스트 콘텐츠는 Olivia Grant 또는 해당 팟캐스트 플랫폼 파트너가 직접 업로드하고 제공합니다. 누군가가 귀하의 허락 없이 귀하의 저작물을 사용하고 있다고 생각되는 경우 여기에 설명된 절차를 따르실 수 있습니다 https://ko.player.fm/legal.

Join us today as we speak to Dr David Tumbarello, from the University of Southampton, as he talks to us about his dynamic and varied academic career that has taken him from New York, to Southampton, stopping off at a number of places in between!! David's lab currently focuses on understanding the cellular mechanisms and molecular machinery required for subcellular trafficking of membrane associated and cytosolic cargo via endocytosis and autophagy. Knowledge of these mechanisms is critical for understanding the molecular mechanisms of cancer and neurodegenerative diseases , which stem from defects in various membrane trafficking and cell signalling pathways.

Today we discuss one of David's lab's recent papers, published June 2020, which looks at multiple mitochondrial quality control pathways that exist to maintain the health of mitochondria, the mitochondrial stress response and identify the interaction of molecules associated with this response with E3 ubiquitin ligase Parkin - involved in Parkinson's disease.

Read the paper here: https://eprints.soton.ac.uk/438725/

Find David on Twitter here: @DavidTumbarello

Check out Biobox Analytics here, the ideal platform for working with NGS data, running and designing bioinformatic pipelines and generating the perfect plots: https://biobox.io/

  continue reading

34 에피소드

Artwork
icon공유
 
Manage episode 288180034 series 2859702
Olivia Grant에서 제공하는 콘텐츠입니다. 에피소드, 그래픽, 팟캐스트 설명을 포함한 모든 팟캐스트 콘텐츠는 Olivia Grant 또는 해당 팟캐스트 플랫폼 파트너가 직접 업로드하고 제공합니다. 누군가가 귀하의 허락 없이 귀하의 저작물을 사용하고 있다고 생각되는 경우 여기에 설명된 절차를 따르실 수 있습니다 https://ko.player.fm/legal.

Join us today as we speak to Dr David Tumbarello, from the University of Southampton, as he talks to us about his dynamic and varied academic career that has taken him from New York, to Southampton, stopping off at a number of places in between!! David's lab currently focuses on understanding the cellular mechanisms and molecular machinery required for subcellular trafficking of membrane associated and cytosolic cargo via endocytosis and autophagy. Knowledge of these mechanisms is critical for understanding the molecular mechanisms of cancer and neurodegenerative diseases , which stem from defects in various membrane trafficking and cell signalling pathways.

Today we discuss one of David's lab's recent papers, published June 2020, which looks at multiple mitochondrial quality control pathways that exist to maintain the health of mitochondria, the mitochondrial stress response and identify the interaction of molecules associated with this response with E3 ubiquitin ligase Parkin - involved in Parkinson's disease.

Read the paper here: https://eprints.soton.ac.uk/438725/

Find David on Twitter here: @DavidTumbarello

Check out Biobox Analytics here, the ideal platform for working with NGS data, running and designing bioinformatic pipelines and generating the perfect plots: https://biobox.io/

  continue reading

34 에피소드

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