Genetic Testing Cavaliers for Heart Disease

The Functional Breeding Podcast

The Functional Dog Collaborative에서 제공하는 콘텐츠입니다. 에피소드, 그래픽, 팟캐스트 설명을 포함한 모든 팟캐스트 콘텐츠는 The Functional Dog Collaborative 또는 해당 팟캐스트 플랫폼 파트너가 직접 업로드하고 제공합니다. 누군가가 귀하의 허락 없이 귀하의 저작물을 사용하고 있다고 생각되는 경우 여기에 설명된 절차를 따르실 수 있습니다 https://ko.player.fm/legal.

2M ago 30:15

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This episode is just me (Jessica Perry Hekman, DVM, PhD) - talking about a new genetic test for the risk of mitral valve disease in Cavalier King Charles Spaniels. Cavs are at incredibly high risk of this disease and get it at much younger ages than other breeds. What does this new test mean in terms of predicting if your Cav is at risk, and whether a particular Cav should be bred?

I talk about several papers in this episode. If you want to check them out yourself, they are:

Mead, Sophie E., et al. "Genetic Variants at the Nebulette Locus Are Associated with Myxomatous Mitral Valve Disease Severity in Cavalier King Charles Spaniels." Genes 13.12 (2022): 2292. - https://pmc.ncbi.nlm.nih.gov/articles/PMC9778376/
Mattin, M. J., et al. "Prevalence of and risk factors for degenerative mitral valve disease in dogs attending primary‐care veterinary practices in England." Journal of Veterinary Internal Medicine 29.3 (2015): 847-854. - https://onlinelibrary.wiley.com/doi/full/10.1111/jvim.12591
Keene, Bruce W., et al. "ACVIM consensus guidelines for the diagnosis and treatment of myxomatous mitral valve disease in dogs." Journal of veterinary internal medicine 33.3 (2019): 1127-1140. - https://pmc.ncbi.nlm.nih.gov/articles/PMC6524084/

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