This Week in Virology: TWiV 1176: Clinical update with Dr. Daniel Griffin

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In his weekly clinical update, Dr. Griffin continues his discussion of whether the mysterious respiratory illness in the Congo is malaria, and in conjunction with your host Vincent Racaniello discusses how routine childhood immunizations especially that against poliovirus are threatened by Robert F Kennedy Jr and Aaron Siri, the origin of the SAR-CoV-2 virus and retraction of Didier Raoult’s research, then returns to discussing the first case of severe disease following H5N1 infection in humans and the state of California’s “bird flu emergency”, the benefit of the measles vaccine, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, how vaccination reduced hospitalization of children between 5-17 years, the ACIP recommendation for the immunocompromised, where to find PEMGARDA, information for Columbia Unversity Irving Medical Center’s long COVID treatment center, long COVID in cancer patients and the physical malaises of long COVID.

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Links for this episode

• Mystery disease in DRC kills mostly children (ALJAZEERA)
• Malaria—mysterious disease in DRC? (ALJAZEERA)
• Mysterious disease in DRC is severe malaria (ALJAZEERA)
• Confirmed first severe human H5N1 case (CIDRAP)
• California declares bird flu emergency (Reuters)
• RFK’s lawyer asks FDA to revoke approval of the polio vaccine (NY Times)
• NO WAY! Vaccination promotes survival and health? (LANCET)
• 10.6 million cases of measles this year alone! (WHO)
• 20% rise in measles…..(NY Times)
• No Sars-CoV-2 relatives in Shi Zhengli’s freezers (Nature)
• Controversial COVID study that promoted unproven treatment retracted after four-year saga (Nature)
• Influenza weekly surveillance report: clift notes (CDC FluView)
• Waste water scan for 11 pathogens (WastewaterSCan)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• US respiratory virus activity (CDC Respiratory Illnesses)
• COVID-19 deaths (CDC)
• COVID-19 national and regional trends (CDC)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• BNT162b2 XBB Vaccine for COVID-19 Among Children 5-17 Years ofAge (JAMA Network)
• ACIP recommendations for those over 65 years and those under 6 months who are immunocompromised (CDC MMWR)
• Where to get pemgarda (Pemgarda)
• EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Fusion center near you….if in NY (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Drug interaction checker (University of Liverpool)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
• Managing healthcare staffing shortages (CDC)
• Steroids, dexamethasone at the right time (OFID)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin’s evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia : Columbia University Irving Medical Center)
• Post-acute sequelae of COVID-19 in cancer patients: Two cohorts in UK and Hong Kong(Cancer Medicine)
• Skeletal muscle adaptations and post-exertional malaise in long COVID (Cell: Trends in Endocrinology & Metabolism)
• Letters read on TWiV 1176
• Dr. Griffin’s COVID treatment summary (pdf)
• Timestamps by Jolene. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to [e-mail]