#15: The First Principles Approach to Not Dying | Bryan Johnson

First Principles with Christian Keil

First Principles and Christian Keil에서 제공하는 콘텐츠입니다. 에피소드, 그래픽, 팟캐스트 설명을 포함한 모든 팟캐스트 콘텐츠는 First Principles and Christian Keil 또는 해당 팟캐스트 플랫폼 파트너가 직접 업로드하고 제공합니다. 누군가가 귀하의 허락 없이 귀하의 저작물을 사용하고 있다고 생각되는 경우 여기에 설명된 절차를 따르실 수 있습니다 https://ko.player.fm/legal.

1+ y ago 46:57

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Today’s episode is brought to you by Strata. Modernize your IAM with Identity Orchestration. Visit https://strata.io/firstprinciples to learn more!

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Episode 15: Bryan Johnson spends $2m/year to not die. But this is more than just a health craze — it’s the birth of a new, secular religious movement. Here’s what Bryan believes.

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(00:00) - Introduction
(01:13) - Zeroth Principles Thinking: Going Beyond First Principles
(04:05) - The Journey to "Don't Die": Bryan's Thought Experiments and Realizations
(07:28) - Is "Don't Die" a Religion? Examining the Parallels
(10:40) - Bryan's Roles in "Don't Die": Philosopher, Embodiment, Message Bearer
(13:05) - Sponsor Break
(14:08) - Quantifying Death: Introducing "Die Scores" for Behaviors and Choices
(17:03) - What is Death and What is Aging? A First Principles Perspective
(19:40) - Measuring Biological Age: Organ by Organ Analysis of Bryan's Body
(23:48) - The Penis as a Marker of Overall Health and Vitality
(26:33) - Epigenetic Clocks and the Pace of Aging Calculated Tests
(30:18) - Bryan's Experience with Follistatin Gene Therapy
(32:25) - Kernel: Building a Mass Market Brain Interface with Time-Domain FNIRS
(36:48) - The Power Law Interventions: Identifying the Most Effective Longevity Levers
(39:22) - Assembling a Team of Scientific Misfits to Tackle Aging
(41:05) - Dreaming Up Ideas: Bryan's Nocturnal Creativity
(42:15) - Telomeres and the Risks of Telomerase Gene Therapy
(44:38) - Reflections on the Challenges of Commercializing Deep Tech
(46:29) - Conclusion: Banding Together to Build an Amazing Future

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Links:

Christian Keil – https://twitter.com/pronounced_kyle
Bryan Johnson - https://x.com/bryan_johnson
Bryan Johnson Personal Website - https://www.bryanjohnson.com/
Blueprint - https://blueprint.bryanjohnson.com/

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Production and marketing by The Deep View (https://thedeepview.co). For inquiries about sponsoring the podcast, email [email protected]

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Checkout the video version here → http://tinyurl.com/4fh497n9

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