Welcome to Our Skin, a Personal Discovery Podcast. Each week, host Holly Frey showcases a personal story from someone who lives–and thrives!--while managing psoriasis. Being diagnosed with a chronic skin condition can throw anyone off track, but Our Skin guests have a message of hope: a diagnosis can be an opportunity to discover new things about ourselves, our grit, and our power. In addition to these tales of hope, Frey and her guests plunge into the jaw-dropping, bizarre, and occasionally ...
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Dr. Hussien Heshmat에서 제공하는 콘텐츠입니다. 에피소드, 그래픽, 팟캐스트 설명을 포함한 모든 팟캐스트 콘텐츠는 Dr. Hussien Heshmat 또는 해당 팟캐스트 플랫폼 파트너가 직접 업로드하고 제공합니다. 누군가가 귀하의 허락 없이 귀하의 저작물을 사용하고 있다고 생각되는 경우 여기에 설명된 절차를 따르실 수 있습니다 https://ko.player.fm/legal.
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Cardio Buzz
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Dr. Hussien Heshmat에서 제공하는 콘텐츠입니다. 에피소드, 그래픽, 팟캐스트 설명을 포함한 모든 팟캐스트 콘텐츠는 Dr. Hussien Heshmat 또는 해당 팟캐스트 플랫폼 파트너가 직접 업로드하고 제공합니다. 누군가가 귀하의 허락 없이 귀하의 저작물을 사용하고 있다고 생각되는 경우 여기에 설명된 절차를 따르실 수 있습니다 https://ko.player.fm/legal.
A channel for cardiology news and updates.
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48 에피소드
모두 재생(하지 않음)으로 표시
Manage series 3473125
Dr. Hussien Heshmat에서 제공하는 콘텐츠입니다. 에피소드, 그래픽, 팟캐스트 설명을 포함한 모든 팟캐스트 콘텐츠는 Dr. Hussien Heshmat 또는 해당 팟캐스트 플랫폼 파트너가 직접 업로드하고 제공합니다. 누군가가 귀하의 허락 없이 귀하의 저작물을 사용하고 있다고 생각되는 경우 여기에 설명된 절차를 따르실 수 있습니다 https://ko.player.fm/legal.
A channel for cardiology news and updates.
…
continue reading
48 에피소드
모든 에피소드
×Is low blood pressure hindering your heart failure treatment? How do you balance life-saving medications with hypotension? We explore the definitions, causes, and practical solutions to optimize patient care. Learn how to navigate ARNI, beta-blockers, SGLT2 inhibitors, and MRAs effectively.
In this episode of Cardio Buzz, we explore the intriguing concept of the 'legacy effect' of medications like those used in treating diabetes, hypertension, hypercholesterolemia, and chronic kidney disease. We'll delve into landmark studies like the UKPDS, Steno-2, and more, examining the lasting impacts of medications such as Repatha, Candesartan, and Empagliflozin. Learn how these drugs contribute to disease regression, modify genes, and prevent non-fatal events to grant long-term protective effects. 00:00 Introduction: The Challenge of Lifelong Medication 00:57 Exploring the Legacy Effect of Medications 01:33 Diabetes Medications: Long-Term Benefits 03:15 Hypertension Medications: Persistent Effects 03:58 Cholesterol Medications: Lasting Impact 04:49 Kidney Disease Medications: Prolonged Benefits 06:12 Understanding the Legacy Effect Mechanism 09:13 Implications and Final Thoughts…
"This week, we delve into the complexities of Familial Hypercholesterolemia (FH) diagnosis and challenge the conventional Dutch Lipid Clinic Network Score. 🩺 Our analysis of a recent Austrian study reveals significant limitations in the score's practical application, including inconsistent scoring and poor record completion. 📝 Key findings: 📊 A single off-treatment LDL cholesterol level of 190 mg/dL demonstrates comparable, and potentially superior, performance to the complex Dutch Lipid Score in identifying individuals with genetically confirmed FH. ✅ This simplified approach offers enhanced index case identification and facilitates timely referrals for genetic testing. 💡 We explore how a simpler, LDL-focused strategy could change clinical practice. This episode is crucial for cardiologists and lipid specialists seeking to streamline FH screening and improve patient outcomes. 🎧 Tune in to learn more! We also discuss the need for further studies to validate this approach and assess its impact on diagnosis rates and cardiovascular outcomes. 🔬 Listen now to 'Ditching the Dutch: FH Diagnosis made easy' and join the conversation on the future of FH screening. #Cardiology #FH #Lipidology #MedicalResearch #ClinicalPractice #Diagnosis 🗣️"…
Join us in this episode of Cardio Buzz as we bring you the latest updates from the European Society of Cardiology conference held in London. Discover groundbreaking clinical trials and new guidelines that promise to reshape the practice of cardiology. We will break down the ten most impactful clinical trials and four new guidelines on hypertension, chronic coronary disease, atrial fibrillation, and peripheral/aortic diseases. Stay ahead in your field with our concise and insightful analysis. Subscribe, like, and hit the notification bell to stay informed on all cardiology advancements. 00:00 Introduction to the European Society of Cardiology Conference 00:59 Top 10 Late-Breaking Clinical Trials 04:41 New Guidelines Overview 05:38 Hypertension Guidelines 09:30 Chronic Coronary Artery Disease Guidelines 15:08 Peripheral Arterial and Aortic Disease Guidelines 20:33 Atrial Fibrillation Guidelines 23:58 Conclusion and Next Steps…
In this episode of Cardio Buzz, the discussion focuses on the potential of stem cell therapy to transform cardiology. Host Dr. Hussain interviews Dr. Yahya Kiwan, an experienced cardiologist and stem cell research advocate. They explore the application of stem cells in treating advanced heart conditions, including post-myocardial infarction and chronic heart failure. The episode covers the sources of stem cells, their harvesting and injection techniques, clinical trial results, and success stories. Dr. Kiwan addresses the ethical considerations and the future of regenerative medicine, emphasizing the need for greater awareness and education in the field. The episode concludes with information on upcoming educational opportunities and fellowships in regenerative cardiology. 00:48 The Promise of Stem Cells in Cardiology 01:31 Interview with Dr. Yahya Kiwan 04:13 Sources and Types of Stem Cells 05:55 Stem Cell Therapy Techniques 10:45 Current Applications and Success Stories 17:18 Future Perspectives and Ethical Considerations 19:38 Learning More About Regenerative Medicine 21:20 Conclusion and Next Steps…

1 From Basic to Advanced: Unpacking Resuscitation (CPR) Challenges with Dr. Naeem Toosy 18:31
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In this episode of CardioBuzz, host Dr. Hussien discusses advanced CPR techniques and challenges from a cardiologist's perspective, featuring Dr. Naeem Toosy, a consultant in emergency medicine. The conversation delves into critical aspects like when to stop resuscitation, use of mechanical circulatory support devices, and the effectiveness of mechanical chest compression devices. Dr. Tusi outlines the significance of early recognition, the role of the public in initiating CPR, and the potential benefits of ECMO during CPR. He underscores the need for national-level education on CPR and the importance of the Good Samaritan law in encouraging public intervention during cardiac arrests. 00:00 Introduction to CardioBuzz 00:08 Overview of CPR Challenges 00:33 Introducing Dr. Naeem Toosy 01:36 Importance of Brain Resuscitation 03:11 When to Stop Resuscitation 06:20 Mechanical Chest Compression Devices 07:49 ECMO in CPR 13:04 National Strategies to Reduce Cardiovascular Mortality 18:04 Conclusion and Final Thoughts…

1 "From Beetroot to Breakthrough: Dr. Daniel Jones’ Findings on Preventing Contrast Nephropathy" 15:27
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In this episode of Cardio Buzz, host and guest Dr. Daniel Jones discuss contrast nephropathy, a kidney injury caused by contrast agents used in medical imaging, and a promising intervention to reduce its incidence. Dr. Jones explains that inorganic nitrates, which are naturally found in green leafy vegetables, have shown significant potential in preventing contrast-induced nephropathy and associated acute kidney injuries in a recent study. This study involved 640 high-risk patients and demonstrated that inorganic nitrates reduced kidney injuries by 60% and improved long-term cardiovascular outcomes. The episode concludes with a conversation about the practical implications and future research plans for this intervention.…
Microplastics are small pieces of plastic less than five millimeters in size that result from the degradation of larger plastic items. Derived from synthetic materials such as polyethylene and polyvinyl chloride, plastics are known for their durability and low cost but pose significant environmental and health risks due to their inability to biodegrade. Microplastics, including even smaller nanoplastics, are found everywhere - in our food, water, air, and even within the human body, where they can be ingested, inhaled, or absorbed through the skin. Italian researchers published their work in March 2024, found microplastics in the atherosclerotic plaques of patients with carotid artery stenosis. This presence of micro and nanoplastics was associated with higher levels of inflammation and an increased risk of heart attacks and strokes. While this finding indicates a correlation rather than causation, it raises concerns about the potential health impacts of microplastics. We provide practical advice on minimizing exposure to microplastics, such as avoiding single-use plastics, choosing products with minimal or no plastic packaging, and opting for natural fibers over synthetic ones. 00:00 Introduction to Plastics: Types and Properties 00:26 The Environmental and Health Impact of Microplastics 01:39 Investigating Microplastics in Human Arteries: A Groundbreaking Study 02:25 Study Findings: Microplastics in Atherosclerotic Plaques 03:12 Implications of the Study: Association vs. Causation 03:44 Practical Steps to Minimize Microplastic Exposure 04:47 Conclusion: The Challenge of Avoiding Microplastics…
With #diabetes projected to affect 783 million patients globally, understanding its connection to #coronary disease, #heartfailure , and #kidneydisease is crucial. We explore the latest guidelines from the European Society of Cardiology and break down the essentials, from diabetes diagnosis to cardiovascular risk assessment, lifestyle modifications, glucose-lowering medications, and other topics. #heart #healthcare #medicine #doctor #nurse #medical #coronavirus #covid19 #healthylifestyle #hospital #mentalhealth #dentistry #pharmacy #surgery #healthtips #weightloss #fitness #workout #diet #nutrition #exercise #wellness #selfcare #prevention #disease #treatment #research…
لدينا جميعاً شعور أن حالات الموت المفاجئ ☠️ دون سابق إنذار قد زادت بين أوساط الشباب والرياضيين 🏃♂️🏃♂️ وعندما اجتاحتنا الكورونا 😷😷😷 في سنة ألفين وعشرين وزادت معها معدل الوفيات طبعا وزاد معها شعورنا بكثرة حالات الموت المفاجئ ونسبها البعض الى الكورونا نفسها ونسبها البعض الآخر للتطعيمات أو اللقاحات واختلط في ذلك العلم.. بتأويلات مدّعي العلم وبنظريات المؤامرة فهل هناك علاقة بين الإصابة بالكورونا والموت المفاجئ وماذا عن اللقاحات وأثرها؟💉💉 الإجابة المباشرة والقصيرة هي نعم هناك ارتباط بين الإصابة بالكورونا وأمراض القلب والموت المفاجئ 💔💔❤️🩹 ونعم هناك ارتباط بين لقاحات الكورونا وبعض أمراض القلب 💔 ولكن دعونا نبدأ القصة من البداية…
في قديم الزمان ، كان البشر يعتقدون أن أقدارهم محددة في النجوم والأفلاك والكواكب ولايزال الكثير ممن أعرفهم يعتقدون أن أبراجهم الفلكية ترسم شخصياتهم وتحدد مصيرهم في الحياة أما في الطب الحديث، وبدلاً من رسم خرائط الأبراج الفلكية ، يمكننا رسم خرائط للجينات. وقد خريطة الجينات هذه على التنبؤ بمن سيمرض ومتى سيمرض وبأي مرض سيصاب. ولكن أيهما أكثر تأثير على خطر الإصابة بأمراض القلب؟ جودة الجينات أم جودة العادات؟ هل يمكن إن وَرّثنا آباؤنا طفرات جينية واقية أن تحمينا من أثر العادات الصحية السيئة؟ وعلى العكس هل يمكن لنمط الحياة الصحي أن يحد من تأثير الطفرات الجينية المؤذية الموروثة؟…
Welcome to ESC this year from Amsterdam, the city known of charming canals, cycling, and attractive architecture. There were 5 new guidelines, tens of session and 30 late-breaking clinical trials. In this episode, I've handpicked just seven trials. The choice was made based on the importance of the topics, the ability of the results to shake up the practice and challenge some cardiology dogmas. Some of the trials were positive, others were negative, but we learn in both cases. I'll be presenting the trials in ascending order of importance, saving the most impactful one for last. Here we go...…
هل يجب أن نتناول الأسبرين بعد سن الأربعين لمنع النوبات القلبية والسكتات الدماغية أم لا؟ هل هو مفيد أم مضر؟
تستوستيرون هو هرمون الذكورة الذي يمنح الرجال القوة والدافع والعزيمة لتحقيق الأهداف. انخفاض مستويات التستوستيرون يؤدي الى فتور الرغبة الجنسية وضعف الانتصاب والإرهاق وضعف العضلات والاكتئاب والدوار وانخفاض كثافة العظام. هل يؤثر ذلك على صحة القلب؟ ماذا يحدث إذا قمنا بتصحيح نقص التستوستيرون باستخدام التستوستيرون الخارجي؟ هل سيؤذي القلب أم يشفيه؟ ماذا تخبرنا أحدث الأبحاث عن تعويض التستوستيرون وتأثيره على القلب؟…
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Cardio Buzz

Hypertension affects one third of humans. Untreated hypertension, shortens life expectancy by five years because it's a major cause of heart failure, renal failure, strokes, and coronary disease. The mortality due to hypertension has increased more than 30% in the last three decades. And the sad fact is that hypertension is uncontrolled in the majority of hypertensive patients, but it seems there's a breakthrough treatment. Angiotensinogen is a protein, it's mainly produced by the liver. If we stop the production of Angiotensinogen in the liver, then the whole. Renin angiotensin system will be silenced. And we have the results of the study on DNA silencing available.…
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Cardio Buzz

Testosterone is the primal essence of manhood. Testosterone is the gift that gives men the strength, the drive, and the resolve to achieve goals. It's part of what makes man a man. But what happens when testosterone levels drop? Does that affect the heart's health? What happens if we correct testosterone deficiency with exogenous testosterone? Will it damage the heart or heal it? What does the latest research on testosterone replacement tell us?…
What is the difference between cholesterol and LDL cholesterol? What evidence do we have that link cholesterol and heart disease? How convincing is that evidence? Is it a myth created by the drug industry or is it a fact backed by science? Let's answer all of these questions in this episode
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Cardio Buzz

1 The Science Behind… How do we know the cause of a disease 12:11
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I've got several questions and comments all related to the cause of atherosclerosis. Most of the questions and comments were skeptical and doubting the causal effect of cholesterol atherosclerosis. In this episode we elaborate more on how modern science arrives at conclusions on the cause of diseases, especially chronic degenerative diseases like atherosclerosis.…
Vaping, or electronic cigarette use, is becoming increasingly popular, especially among youth and young adults. While it is perceived as safer than tobacco cigarettes, the exact composition of the liquids used in e-cigarettes is not publicly known, making it difficult to predict the health effects. E-cigarette contents include nicotine, flavors, chemical additives, and a solvent. Studies have shown that vaping can have negative effects on cardiovascular health, such as higher arterial stiffness, impaired endothelial function, and increased blood pressure. However, clinical studies were inconclusive, and long-term trials were not available. It is also unclear if e-cigarettes can be effectively used for smoking cessation. We reviewed the contents of the vape, the latest literature, and the statement from the American heart association on electronic cigarettes, and here are the facts.…
Lipoprotein a is a molecule produced by the liver, similar to LDL in structure, with a peculiar protein that gives it wide variability. Elevated lipoprotein little (a) is causal of atherosclerotic disease, recurrent strokes, and aortic calcification. Smaller forms of LPa are riskier. LPa is not a risk factor for venous thromboembolism The levels are determined genetically with minimal impact from lifestyle. Normal values are 125 nmol/L) Levels should not be converted from mg to mmol or vice versa Levels should be measured once in the lifetime The excess risk of LPa elevation can be mitigated by additional LDL lowering and tighter CV risk factor control. PCSK9i(s) reduces the levels by 25%, but they are not approved for this indication. Aspirin may be beneficial as primary prevention in individuals with genetic variants that elevate LPa. Specific therapies are being developed to lower LPA by >70% and may be released three years from now.…
Sleep is the single most effective way to reset our brain and body health each day. Sleep is a foundational element of human biology and is a requirement for life. We spend roughly one-third of our lives asleep. A famous quote is, “Happiness is nothing more than getting enough sleep”. Sleep disturbance is a common condition in modern society, with evidence showing that people sleep on average 1.5 hr less than a century ago. one-third of the general population suffers from sleep-related problems And now, we better understand the relationship between poor sleep and poor health, especially cardiovascular health. Just a couple of months ago, the American heart association added Sleep to the essential pillars of cardiovascular health. And in this episode, we will discuss sleep and heart health, what is good sleep, what is bad sleep, what’s the risk of poor sleep, and we will end up with some advice on how to improve your sleep for a stronger heart. First, is there a relationship between the number of hours slept and CV health? Yes, we have clear data on this relationship Sleeping for less than six hours is associated with a 70% increase in mortality Sleeping 5 hr or less per night had a 2.3-fold greater risk of AMI Sleeping for less than four hours is associated with a 2.8 times increase in mortality Sleeping for nine hours or more was also associated with a 70% increase in mortality The ideal duration of sleep is between seven hours and eight hours because this has been associated with the best survival. During normal, healthy sleep, blood pressure drops by around 10-20%. This is known as nocturnal dipping, and research highlights its role in cardiovascular health. When we sleep, the blood pressure comes down, and the heart rate also goes down. This helps to unload the circulatory system and give rest to the heart. Poor sleep, whether from a lack of sleep or sleep disruptions, is associated with non-dipping, meaning that a person’s blood pressure doesn’t go down at night. Studies have found that elevated nighttime blood pressure is related to overall hypertension (high blood pressure). Not only hypertension but sleep disruption is also associated with an increased risk of diabetes, coronary atherosclerosis, and myocardial infarction. Add to that obesity risk; we can remember that we are more likely to feel hungry when we don’t get enough sleep. All these conditions are increased with sleeping less than six hours or with sleeping more than nine hours. It is a U-shaped relation. We've understood the impact of sleep quantity on health, but what is the impact of poor sleep quality on health? We also know that difficulty falling asleep, nightmares, easily awakening from sleep, use of sleeping pills, and walking up tired are markers of poor sleep. Poor sleep quality was associated with subclinical cardiovascular disease and increased risk of cardiovascular disease. Sleep apnea, where there is airway obstruction resulting in loud snoring and apnea, is a well-established risk for resistant hypertension, heart failure, coronary disease, and atrial fibrillation. What’s the mechanism linking sleep and poor cardiometabolic health? There are several potential mechanisms. Data show that a lack of sleep may increase sympathetic nervous system activity the next day; sleep deprivation also results in an inflammatory state and in increased salt intake, elevated cortisol levels, and insulin resistance. These changes all culminate in poor cardiometabolic health resulting in a cascade or a package of cardiovascular diseases. How to improve your sleep? First: Identify your ideal sleep duration The general rule is 7-8 hours of daily sleep. But because this may vary, you can measure your own needed sleep hours this way… Try to get into bed at the time where you fall asleep within about 15 minutes, and wake up without an alarm clock, feeling rested, and having enough energy to carry you through the day. On average, the amount of sleep you get this way is probably the right amount of sleep for you. The American heart association elected to add sleep duration as an eighth metric to the formal definition of CVH. Metric: Average hours of sleep per night Scoring:Points Level 100 7–…
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Cardio Buzz

How can wearables and smartwatches guide the diagnosis and management of serious arrhythmias like atrial fibrillation and ventricular tachycardia?
Athletes also can have heart disease and can collapse in the field. How can wearable digital devices help an athlete who has suspected arrhythmia?
Smart gadgets are all around, in TVs, phones, cameras, cars, kitchens, and also on our skin! Bands, watches, rings, earbuds, and even shirts can monitor our bodies and give insights into our health and disease. The global Wearable Technology Market size was worth about 115.8 (USD billion) in 2021 and is predicted to grow to around 380.5 (USD billion) by 2028 Wearables can measure the pulse and can even tell the heart rhythm. How can wearable technology’s ability to monitor rate and rhythm help in medicine? How accurate are they? Can physicians rely on them in the diagnosis and treatment of abnormal heart rhythms (arrhythmia)? The European heart rhythm association (EHRA) has recently released a practical guide on the use of digital devices to detect and manage arrhythmia and we are here to review it. I will not discuss medical devices such as Holter monitors or implantable devices that can deliver therapy such as pacemakers and life vests as they are well established, are prescribed and used by a physician, and fall outside the scope of this episode. We will give an overview of Devices that anyone can buy and use outside the hospitals; types and advantages of each Clinical application to evaluate palpitation…
How to tailor medicine for each and every individual person? Mixing clinical variables, genetic variants, and molecular profiles, all into Artificial Intelligence can lead to "Precision Medicine"... Interviewing Prof Maha Saber-Ayad, Professor of Pharmacology at Sharjah University on Pharmacogenomics and the quest for precision medicine.…
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Cardio Buzz

Paris is not only the city of light, love, and culture but it is also the home of the biggest interventional cardiology meeting Paris Course on Revascularization PCR. Last week, the meeting was back in person after two years of COVID-imposed virtual attendance. Eight thousand attendees inside the “Palais de Congress”, tens of sessions, live cases, and industry stands. This version of Euro PCR celebrated 30 years of radial cath and 20 years of transcatheter aortic valve interventions (TAVI). I had the chance to attend, meet the experts, and present my cases. And I am here bringing to the cardio buzz audience, who couldn’t make it to the conference, the hot topics, and the latest breaking trials from Paris. 7. Robots invade the cath lab 6 Simulate before you operate 5 Leaving nothing behind 4 Fewer wires in, more data out 3 How long will the valve live? 2 Snuff boxers punched in the DISCO 1 A Patch to Stop Bleeding…
Drawing a map of genes might help us predict who will get sick and when we will get sick of heart disease or cancer. And we have seen Angelina Jolie, the famous actress, going for a preventive mastectomy because she had a faulty gene for breast cancer. But Is it the inevitable destiny, or can we change it? Do genes decide who will have heart disease? Who is to be blamed for heart disease? The genes we inherit, or the environment where we grow and live?Can your good genes protect you from your unhealthy lifestyle? Can a good lifestyle buffer our faulty genes?Watch it 🎦 on YouTube Read 📖it on LinkedIn ReferencesCirculation. 2022;145:808–818. DOI: 10.1161/CIRCULATIONAHA.121.053730 https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.121.053730…
With all its health benefits, cheap, and with few side effects, Aspirin is in every house. Aspirin reduces mortality in acute myocardial infarction. It is intuitive to use it for prevention, not only for treatment. Some studies supported that practice.But in the 21st century, we realize that aspirin is a gastric irritant and can cause bleeding. We got better pain killers and more potent platelet inhibitors, and we started questioning aspirin's protective effect compared to other drugs. So what’s the truth about Aspirin? Should people above 40 with no heart or vascular disease take Aspirin to prevent heart attacks and strokes or not? LinkedIn articleYouTube VideoAspirin Use to Prevent Cardiovascular Disease: US Preventive Services Task Force Recommendation Statement.” JAMA 327, no. 16 (April 26, 2022): 1577–84. https://doi.org/10.1001/jama.2022.4983https://www.cvriskcalculator.comhttps://www.uspreventiveservicestaskforce.org/uspstf/recommendation-topics…
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