최고 Beyond The Abstract 팟캐스트 (2024)

1
Going Nuts About New Treatments for Food Allergies 14:43

3d ago14:43

14:43

Food allergies are a major problem – common, potentially deadly, and without effective medicines to prevent them from occurring. But earlier this year, researchers and doctors published a clinical trial reporting an effective new treatment for preventing allergic food reactions. In today’s episode of Beyond the Abstract, Derek and Dan dive into the…

1
Xylazine Use Among People Who Inject Drugs, Philadelphia 2022 13:47

23d ago13:47

13:47

Xylazine Use Among People Who Inject Drugs, Philadelphia 2022 Host Shawn McNiel, MD, is joined by Marissa Tan, DO, an Epidemiology Intelligence Service (EIS) Fellow for the Center of Disease Control and Prevention through the Philadelphia Department of Public Health. Dr. Tan and her co-authors sought to help clinicians better identify individuals a…

1
Xenotransplantation: How Pig Kidneys are Saving Human Lives 13:26

1M ago13:26

13:26

Thousands of patients in the US die every year waiting for an organ transplant, often because there are not enough human organ donors. Xenotransplantation — transplantation from another species to humans — could solve this problem, but has remained the realm of science fiction given many technical obstacles. Now, with advances in gene editing, this…

1
From Stigma to Science: A Scientist's Journey to Treat Hyperemesis Gravidarum 19:49

3M ago19:49

19:49

While almost all women experience nausea and vomiting during pregnancy, few are debilitated by severe symptoms: a condition known as hyperemesis gravidarum (HG). HG has been stigmatized and neglected by the biomedical community, with limited research funding for developing effective treatments. In this episode of Beyond the Abstract, Derek and Dan …

1
Exploring the Impact of Opioid Settlements on Addiction Medicine 26:29

4M ago26:29

26:29

Podcast host Shawn McNeil, MD, is joined by Joshua Sharfstein, MD, and Sara Whaley, MPH, from Johns Hopkins Bloomberg School of Public Health who delve into the strategic allocation of $56 billion from opioid litigation settlements. As they discuss the principles for effective fund utilization, they highlight opportunities for addiction medicine sp…

1
The Way of Wegovy Part 2: Obesity Treatment and New Frontiers 22:53

5M ago22:53

22:53

A new class of medicines has transformed the treatment of obesity -- Wegovy and Ozempic have become household names. While we discussed these GLP-1 medicines on an episode of Beyond the Abstract less than a year ago, the field has progressed so quickly we thought it was already time to review many of these recent developments. In today's episode, D…

1
Association of Urine Fentanyl Concentration With Severity of Opioid Withdrawal Among Patients Presenting to the Emergency Department 12:42

5M ago12:42

12:42

In episode 28 of Addiction Medicine: Beyond the Abstract, host Shawn McNeil, MD is joined my Ashish Thakrar, MD, MS, an addiction medicine specialist and Assistant Professor of Medicine with the University of Pennsylvania. Dr. Thakrar discusses the outcome of his research, which aimed to determine whether fentanyl concentration is associated with t…

1
Incidence and Disparities in Use of Stigmatizing Language in Clinical Notes for Patients With Substance Use Disorder 11:06

7M ago11:06

11:06

The language used to describe people with substance use disorder impacts stigma and influences clinical decision-making. Host Dr. Shawn McNeil, MD discusses with Dr. Scott G. Weiner, MD the presence of stigmatizing language in clinical notes and detects patient- and provider-level differences. ----more---- Based on original research published in th…

1
Incidence and Disparities in Use of Stigmatizing Language in Clinical Notes for Patients With Substance Use Disorder 12:06

7M ago12:06

12:06

The language used to describe people with substance use disorder impacts stigma and influences clinical decision-making. Host Dr. Shawn McNeil, MD discusses with Dr. Scott G. Weiner, MD the presence of stigmatizing language in clinical notes and detects patient- and provider-level differences. Based on original research published in the Journal of …

1
ChatGPT Will See You Now: The Present and Future of AI in Medicine 18:52

7M ago18:52

18:52

Debates around artificial intelligence are everywhere: will ChatGPT usher in a new era of productivity and creativity? Or will advanced AI replace millions of workers? Doctors have similar questions about how AI may influence medicine. In today's episode of Beyond the Abstract, Dan and Derek take a deep dive into all things AI and health. They disc…

1
Examining the Primary Care Experience of Patients With Opioid Use Disorder: A Qualitative Study 18:06

9M ago18:06

18:06

Examining the Primary Care Experience of Patients With Opioid Use Disorder: A Qualitative Study In episode 26 of Addiction Medicine: Beyond the Abstract, host Shawn McNeil, MD, is joined by Michael Incze, MD, MSEd. Dr. Incze is a primary care physician at the University of Utah Health Division of General Internal Medicine. He is board certified in …

1
Defining the Heart-Brain Axis 13:23

10M ago13:23

13:23

It's well known that emotions can affect the heart - we've all had an anxiety-producing thought that leads to the feeling of our heart pounding out of our chest. But what about the opposite: can the heart control our emotions? In today's episode of Beyond the Abstract, Derek and Dan discuss a fascinating new study looking at whether making the hear…

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Meet New JAM Editor-in-Chief, David A. Fiellin, MD, FASAM 14:08

10M ago14:08

14:08

Meet JAM Editor-in-Chief, David A. Fiellin, MD, FASAM Dr. Fiellin is an internist, board certified in addiction medicine. He is professor of Medicine and Emergency Medicine at Yale School of Medicine, and Public Health at Yale School of Public Health; vice chief of Faculty Affairs for the Department of Internal Medicine’s Section of General Interna…

1
'Cause Baby Now We've Got Bear Blood 19:33

12M ago19:33

19:33

The effect of inappropriate blood clotting can be devastating, including heart attack and stroke. While there are many medications to reduce the risk of clotting, our understanding of why blood clots and when remains incomplete. In today’s episode of Beyond the Abstract, Derek and Dan share the remarkable story of how a team of researchers discover…

1
The Key Lies with APOE: Unlocking New Treatments for Alzheimer's 16:28

1y ago16:28

16:28

Alzheimer’s disease is a devastating neurodegenerative condition affecting millions of people around the world. Current therapies are only partially effective, despite decades of research aimed at understanding the causes of the disease. Alzheimer’s is largely genetic, and the best-known genetic risk factor for Alzheimer’s comes from mutations in a…

1
The Way of Wegovy: A New Drug for Weight Loss 14:41

1+ y ago14:41

14:41

Approximately four in 10 Americans are obese, putting millions at increased risk of developing diabetes, heart disease, liver cancer, and other chronic illnesses. For many years it’s seemed that we’re losing the battle against this modern epidemic. However, the tide may be turning with the recent approval of a revelatory new class of medications. I…

1
BTS on BTA: Answering Your Questions! 32:47

1+ y ago32:47

32:47

Our episode today takes us Behind The Scenes (BTS) on Beyond The Abstract (BTA). Derek and Dan answer your questions on graduate school on everything from how we chose our research topics, how we deal with imposter syndrome and stress, how it feels to have finished our PhDs, and more! We hope you enjoy this change from our usual format. If you have…

1
Runnin' for Clusterin: Exercise Improves Cognition 13:00

1+ y ago13:00

13:00

This episode is sponsored by Proteintech. Exercise is good for us - it keeps off the pounds and decreases our risk for heart attack and diabetes. What may be less known about exercise is that it's actually also good for the brain. Exercise improves memory and learning, and may even improve brain function in people with Alzheimer's disease. However,…

1
The Placenta: Here for a Good Time, Not a Long Time 16:20

1+ y ago16:20

16:20

Preeclampsia is a pregnancy disorder characterized by high blood pressure and contributes to significant fetal and maternal deaths. However, what exactly causes preeclampsia is unclear. It's thought that preeclampsia is caused by placental dysfunction - specifically, the ability of specialized fetal cells called trophoblasts to replace and remodel …

1
Surveillance System for Opioid-Associated Amnestic Syndrome 18:09

1+ y ago18:09

18:09

In episode twenty-four of Addiction Medicine: Beyond the Abstract, host Shawn McNeil, MD is joined by Dr. Jed Barash, a Neurologist from Massachusetts. In his paper, Dr. Barash and his colleagues discuss using an existing syndromic surveillance system to monitor for possible cases of opioid-associated amnestic syndrome in the state of Massachusetts…

1
Revving Up the CAR T: Fighting Fibrosis with Gene Therapy 19:48

2y ago19:48

19:48

CAR T cells have been engineered to treat everything from cancer to scarring in the heart. However, one major barrier to wide-spread therapy is the fact that T cells have to be removed from the patient, engineered, and then putting them back in the patient. But what if we could create a drug that makes CAR T cells inside a patient's own body? This …

1
COVID Shrinks Your Brain 26:53

2y ago26:53

26:53

COVID brain fog is a well-documented, residual symptom following COVID infection. However, how COVID infects the brain and potential causes of COVID brain fog are unclear. In this episode, Dan and Derek discuss two recent studies that show that even mild cases of COVID may have important impacts on brain structure and function. Douaud et al. SARS-C…

1
HIV Preexposure Prophylaxis by Buprenorphine Prescribers 13:00

2y ago13:00

13:00

In episode twenty two of Addiction Medicine: Beyond the Abstract, host Shawn McNeil, MD, is joined by Amy Kennedy, MD, MS. Dr. Kennedy is an Acting Assistant Professor of Medicine at the University of Washington and Director of GMS Addiction Medicine Program at the VA Puget Sound Healthcare System. In her paper, Dr. Kennedy discusses barriers and f…

1
Not Just a Kiss: Mono Increases Risk for Multiple Sclerosis 21:50

2y ago21:50

21:50

Epstein-Barr Virus (EBV) is best known for causing mononucleiosis, or the 'kissing disease,' in teenagers. Almost all adults get EBV at some point in their lives, even if they don't get mono. New research shows that EBV infection may have longer-lasting impacts. Using data from the American military, researchers now show that EBV infection drastica…

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Racial-ethnic Differences in Misuse of Prescription Medications 14:34

2y ago14:34

14:34

February 14, 2022In episode twenty-three of Addiction Medicine: Beyond the Abstract, host Shawn McNeil, MD is joined by Catalina Lopez-Quintero, MD, PhD, MPH. Dr. Lopez-Quintero is an Assistant Professor of Epidemiology at the University of Florida. In her paper, Dr. Lopez-Quintero discusses racial-ethnic differences in reasons for misuse of prescr…

1
Grey Hair, Don't Care 14:33

2+ y ago14:33

14:33

Hair greying is thought to be an irreversible event related to life stress, but the process has never been extensively studied. For the first time, researchers at Columbia University use novel techniques with hair imaging and a daily diary to demonstrate that hair greying is not only associated with stressful life events, but that the process is re…

1
Mind the Placenta: Linking Placenta Dysfunction to Autism 18:01

2+ y ago18:01

18:01

The placenta is a transient organ of pregnancy that supports fetal growth and organ development. Placental dysfunction underlies many developmental defects, but this connection is poorly understood. Furthermore, many neuropsychiatric disorders, such as autism spectrum disorder, are linked to altered brain development and are more common in men than…

1
The Spice is Right: Mobilizing Stem Cells with Capsaicin 13:11

2+ y ago13:11

13:11

Bone marrow stem cell transplants are some of the most important tools in treating diseases like leukemia and multiple myeloma. However, harvesting enough stem cells for transplantation is often a big issue for doctors. Finding new ways to elicit stem cell mobilization from the bone marrow to improve harvesting could go a long way in improving trea…

1
Vibin' Myelin: A Vaccine for Multiple Sclerosis 20:20

2+ y ago20:20

20:20

Multiple Sclerosis (MS) is a devastating autoimmune disease that result from the immune system attacking parts of the nervous system. For a long time, MS has been treated with broad immunosuppression using corticosteroids that puts the patient at risk for infections, but this might soon change. In today's Beyond the Abstract episode, Derek and Dan …

1
Rejection of Referrals Based on Substance Use Diagnosis and Treatment 11:49

2+ y ago11:49

11:49

Addiction Medicine: Beyond the Abstract (Episode 21). Host Shawn McNeil, MD, is joined by Simeon Kimmel, MD, who discusses a trend of referral rejections for post-acute medical care among patients with substance use disorders and patients receiving opioid agonist treatment Dr. Kimmel (@simkimmel) is an Assistant Professor of Medicine at Boston Univ…

1
Skinny Genes 24:56

3y ago24:56

24:56

High cholesterol and clogged arteries are the main cause of heart attacks. While modern medicine has developed ways to keep cholesterol down, these medications must be taken daily in order to be effective and come with their own list of side effects. This is where CRISPR comes in. Scientists have now developed a way to safely and durably reduce cho…

1
Butt Breathing 17:52

3y ago17:52

17:52

When patients have low oxygen levels, doctors use various types of breathing machines to deliver oxygen to the lungs - but it's not always effective. Now, scientists have taken inspiration from a small fish called the loach and developed a method to deliver oxygen through... the butt. This is particularly pertinent in the face of the COVID-19 pande…

1
Mitochondria Actin(g) Wavy 16:49

3y ago16:49

16:49

Mitochondria are known as the powerhouse of the cell because of their important function in producing energy. During cell division (also known as mitosis), a cell has to duplicate everything from its DNA to proteins to organelles - including mitochondria - and distribute them equally between two cells. However, no one really knows how exactly these…

1
Patient-Centeredness of Addiction Treatment Intake 10:12

3y ago10:12

10:12

In episode 20 of Addiction Medicine: Beyond the Abstract, we are joined by Tami Mark, PhD. She is a Senior Fellow of Behavioral Health Financing and Quality Measurement for RTI International. Dr. Mark discusses patient placement criteria for addiction treatment and multidimensional assessments, which was published in the March/April 2021 issue of J…

1
Spilling the CAR-T on Cardiac Fibrosis 20:40

3y ago20:40

20:40

Chimeric antigen receptor (CAR) T cell therapy has revolutionized cancer treatment by engineering our own immune cells to recognize and fight cancers that are resistant to treatments like radiation and chemotherapy. But can we use CAR T cells to treat other diseases too, like cardiac fibrosis? Cardiac fibrosis, or scarring of the heart, is common f…

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Sex Differences Among Adults With Opioid Use Disorder 11:52

3y ago11:52

11:52

In episode 19 of Addiction Medicine: Beyond the Abstract, we are joined by MacKenzie Peltier, PhD. She is an Assistant Professor of Psychiatry at Yale School of Medicine. In her paper, Dr. Peltier discusses sex-specific vulnerabilities observed among individuals with opioid use disorder.저자 Shawn McNeil, MD

1
Let's Talk About Sex-Biased Diseases 29:52

3y ago29:52

29:52

Why do some diseases affect more men than women, or more women than men? Science has been unable to explain many of these sex-biased diseases until just recently. In this episode of Beyond the Abstract, Derek invites Dan Weiner, an MD/PhD student at Harvard Medical School, to talk about a recent breakthrough in neuropsychiatric and autoimmune genet…

1
Avoiding NICU for Newborns With Neonatal Opioid Withdrawal Syndrome 9:56

3+ y ago9:56

9:56

Journal of Addiction Medicine Journal of Addiction Medicine. 14(5):401-408, September/October 2020In episode eighteen of Addiction Medicine: Beyond the Abstract, we are joined by Kimberly Spence, MD. She is an Associate Professor of Pediatrics at the Saint Louis University School of Medicine. In her paper, Dr. Spence discusses the benefits of treat…

1
Computerized CBT for Substance Use Disorders 13:36

3+ y ago13:36

13:36

Journal of Addiction Medicine In episode seventeen of Addiction Medicine: Beyond the Abstract, we are joined by Kathleen Carroll, PhD. She is the Albert E. Kent Professor of Psychiatry at Yale University School of Medicine. In her paper, Dr. Carroll discusses the feasibility of implementing computer-based treatments for substance use disorders in p…

1
Going Nuts for Sir Toli 13:50

3+ y ago13:50

13:50

This week on Beyond the Abstract, Derek and Ellen talk about Derek's newest first-author publication in Developmental Biology. They discuss the role of myosin in Sertoli cells and how mutations can affect male fertility. More importantly, Ellen recounts a science celebrity sighting from our time working at the NIH. This article was featured as the …

1
Antibodies, Mutations, and Sewage... Oh My! 18:45

3+ y ago18:45

18:45

Do declining antibodies to SARS-CoV-2 mean long-lasting immunity is impossible? What do mutations in the virus mean for vaccine effectiveness? Can we use sewage water to monitor the pandemic? On this episode of Beyond the Abstract, Derek and Ellen talk about three recent papers related to these important COVID-19 issues. Note: Since recording this …

1
Back from Beyond (Life Updates!) 8:42

3+ y ago8:42

8:42

After a short break, Derek and Ellen are BACK with a quick update episode! They discuss New Years resolutions, COVID, grad school progress, TV shows watched, and more. Stay tuned for more episodes discussing the latest, cutting-edge research in a way that just about anyone can understand.저자 Beyond the Abstract

1
CRISPR: All About That Base (Editing) 21:18

4y ago21:18

21:18

CRISPR is a genome-editing technology that has revolutionized medical research and created new therapies for previously incurable diseases. But what is CRISPR exactly, where does it come from, and how does it work? In this episode of Beyond the Abstract, Ellen and Derek explore how scientists have created a method of using CRISPR to treat Sickle Ce…

1
A (Cytokine) Storm is Brewing 24:16

4y ago24:16

24:16

COVID-19 is a devastating disease, and the elderly and those with chronic medical conditions are especially at risk. But why is it that some seemingly healthy people also get so sick that they have to be put on a ventilator? The answer may lie in our immune system. This week on Beyond the Abstract, Ellen and Derek explore a new paper that begins to…

1
Opioid Overdose in the Hospital Setting: A Systematic Review 13:14

4y ago13:14

13:14

In episode sixteen of Addiction Medicine: Beyond the Abstract, we are joined by Itai Danovitch, MD, MBA. He is the chairman of the Department of Psychiatry and Behavioral Neurosciences at Cedars-Sinai Medical Center in Los Angeles. In his paper, Dr. Danovitch discusses some of the challenges facing the study of opioid overdose events in the hospita…

1
Panic at the DisCOVID 23:32

4y ago23:32

23:32

In the midst of the coronavirus pandemic, a lot remains unknown about SARS-CoV-2, the virus causing COVID-19. While we race to understand the true nature of the virus and create a vaccine, our best defense against the pandemic is social distancing. Understanding how our immune systems will respond to the virus is key in answering the questions of h…

1
Bubble Lamb 26:11

4y ago26:11

26:11

Extremely premature infants are those that are born at less than 28 weeks, and often weigh less than two pounds at birth. Medical advancements have pushed the limits of viability to permit survival of infants at 22-23 weeks, but these infants suffer from high rates of mortality. Those that survive are all but guaranteed chronic complications relate…

1
Novel Coronavirus 2019 (2019-nCoV) 26:21

4+ y ago26:21

26:21

The novel coronavirus 2019 (2019-nCoV) is a respiratory virus originating from Wuhan, China that has spread to many countries, causing an outbreak. Headlines on its rapid spread have dominated media and news sites globally, and a lot remains unknown about how the virus infects humans, how it spreads, and how deadly it really is. In this episode of …

1
The Golden Phage 32:11

4+ y ago32:11

32:11

Alcoholic hepatitis is a severe, life-threatening type of liver disease, but not for all patients. Some patients seem to have worse outcomes than others, but what differentiates these patients and how do we treat them? In this episode, Derek and Ellen invite Sam McCright, an MD/PhD student at the University of Pennsylvania studying the microbiome, …

1
Integrating Reproductive Health Services into Opioid Treatment Facilities 8:34

4+ y ago8:34

8:34

In episode fifteen of Addiction Medicine: Beyond the Abstract, we are joined by Dr. Tricia Wright, MD, MS, FACOG, DFASAM. She is a professor of clinical medicine at the University of California San Francisco. In her recent commentary, Dr. Wright discusses some of the challenges facing women in opioid treatment programs and the need for the provisio…

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