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The Microscopists is a podcast from Bitesize Bio and ZEISS Microscopy that takes you into revealing, entertaining, and personal meetings with the great microscopists of our time. Your host is Dr Peter O’Toole. Peter will help you understand what drives great, successful scientists, what really inspires them and what they enjoy most in life. This set of candid, fun, and engaging interviews serves not only to help inspire upcoming scientists but to show how career tracks and work-life balance ...
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#72 — Paul Verkade is a Professor of Bioimaging in the School of Biochemistry at the University of Bristol. In this episode of The Microscopists, Paul joins Peter O’Toole to discuss his inspirations and involvement in developing correlative light and electron micropy (CLEM). He also chats about co-establishing the Wolfson Bioimaging Facility and hi…
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#71 — Timo Zimmermann is Team Leader in Light and Microscopy Service and Development at the European Molecular Biology Laboratory (EMBL) Imaging Centre. In this episode of The Microscopists, Timo joins Peter O’Toole to discuss how the microscopy courses they have attended changed their career paths. They also chat about Timo's stunning recent 3D re…
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#70 — In this special panel discussion, Peter O'Toole is joined by members of the Network of European Bioimage Analysts (NEUBIAS), including: • Elnaz Fazeli, Imaging Specialist in the Department of Anatomy at the University of Helsinki. • Kota Miura, freelance image analyst and Vice Chair of NEUBIAS. • Robert Haase, Group Leader in Bio-image Analys…
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#69 — In this special technology focus episode, Peter O'Toole is joined by experts in Fluorescence Correlation Spectroscopy (FCS), including: • Thorsten Wohland, Professor in the Department of Biological Sciences at the National University of Singapore. • Annette Bergter, Marketing Manager, Business Sector Life Sciences at ZEISS Research Microscopy…
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#68 — Beth Cimini is a Senior Group Leader at the Broad Institute of MIT and Harvard. In this episode of The Microscopists, Beth joins Peter O’Toole to discuss the challenges of developing popular software tools like CellProfiler in academia and why harsh peer review leads to user-friendly software. They also chat about why someone on Twitter got m…
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#67 — In this special episode, Peter O'Toole is joined by Executive Board Members of BioImaging North America (BINA), including: • Alison North, Research Associate Professor and Senior Director at The Rockefeller University. • Claire Brown, Associate Professor & Director, Advanced BioImaging Facility at McGill University. • Nikki Bialy, BINA Progra…
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#66 — In this special episode, Peter O'Toole is joined by researchers from the Latin American community, including: • Andres Kamaid, Researcher at the Institut Pasteur de Montevideo. • Leonel Malacrida, Associate Professor and Head of the Advanced Bioimaging Unit at the Universidad de la República & Institut Pasteur de Montevideo. • Mariana De Niz,…
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#65 — Ronald Germain, M.D. is a Distinguished Investigator and Lab Chief of the Lymphocyte Biology Section at the National Institutes of Health. In this episode of The Microscopists, Ron joins Peter O’Toole to discuss why you need to think like a surfer in science. They also chat about what he does to entertain himself when he gets bored in meeting…
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#64 — Jean-Yves Tinevez is a Research Engineer at Institut Pasteur. In this episode of The Microscopists, Jean-Yves joins Peter O’Toole to discuss why he finds supporting other researchers at a core imaging facility so rewarding. They also chat about storing his extensive collection of comic books in his Parisian apartment and some favorite countri…
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#63 — Kedar Narayan (Frederick National Laboratory and National Cancer Institute) joins Peter O’Toole to discuss how he originally wanted to be a designer and never took high school biology because he thought it was icky. They also dive into why developing technologies is demanding and the potential downsides to AI in science. Watch or listen to al…
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#62 — Lucy Collinson (The Francis Crick Institute) and Kirk Czymmek (The Donald Danforth Plant Science Center) join Peter O’Toole to discuss volume EM. Together they highlight what volume EM is, how it has been a quiet revolution, and share resources to help those wanting to get started using this powerful new technology. They discuss how amazingly…
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#61 — Joachim Frank is a Professor of Biological Sciences at Columbia University and winner of the 2017 Nobel Prize in Chemistry for his involvement in the development of CryoEM. In this episode of The Microscopists, Joachim joins Peter O’Toole to discuss how his early interactions with an electron microscope shaped his career and how he considered…
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#60 — In this episode of The Microscopists, Peter O'Toole is joined by three representatives of bioimaging networks in Africa: Caron Jacobs of the African BioImaging Consortium (ABIC), Ben Loos of the South African BioImaging Community (SABI) and Mahmoud Maina of the Biomedical Science Research and Training Centre (BioRTC) at Yobe State University.…
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#59 — Aydogan Ozcan is Chancellor’s Professor and HHMI Professor in the Department of Electrical and Computer Engineering at UCLA Samueli School of Engineering. Aydogan joins Peter to talk about how advances in imaging technology could make security screening less invasive, the importance of communicating science to the public, and why you need to …
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#58 — Laura Waller is Professor in the Department of Electrical Engineering and Computer Sciences at UC Berkeley. In this episode of The Microscopists, Laura joins Peter O'Toole to talk about how she got interested in optics and engineering and what it's like to run a lab. She also talks about her unusual extreme reading hobby, which has seen her r…
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#57 — Michael Albiez is CEO of Carl Zeiss Research Microscopy Solutions. He chats to Peter O'Toole about how Zeiss Microscopy recently won the German Future Prize live on national TV, and he shares what it's like to connect with many different researchers who all use microscopy in their work. We also hear about his aspirations to become a teacher, …
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#56 — Stefan Hell is Director at the Max Planck Institute for Multidisciplinary Sciences in Göttingen and at the Max Planck Institute for Medical Research in Heidelberg. In this episode of The Microscopists, Stefan tells Peter O'Toole about his quest to overcome the diffraction barrier, why he doesn't think of himself as a microscopist, and staying…
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#55 — Emma Lundberg is Associate Professor of Bioengineering at Stanford, Professor in Cell Biology Proteomics at KTH Royal Institute of Technology, and Head of the Subcellular Section of the Human Protein Atlas. Emma joins Peter O’Toole to talk about crowdsourcing image analysis for the Human Protein Atlas program within the EVE Online virtual gam…
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#54 — Florian Jug is Research Group Leader and Head of the Image Analysis Facility at Human Technopole, Milan. Florian joins Peter O'Toole to discuss his research using AI and machine learning to better analyze and quantify biological data. They chat about his early ambitions in computer science, and he tells us why he enjoys teaching various cours…
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#53 — Christian Eggeling is Head of the Department of Biophysical Imaging at the Institute of Photonic Technologies (IPHT, Jena). In this episode of The Microscopists, Christian joins Peter O'Toole to discuss his varied career to date, starting with a degree in physics, a short stint in a biotech company, followed by faculty positions in Oxford and…
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#52 — Wah Chiu is Wallenberg Bienenstock Professor, and Professor of Bioengineering, and Microbiology and Immunology at Stanford University. In this episode of the Microscopists, Wah chats with Peter O' Toole about his pioneering cryoEM work and his research goals of understanding the structural biology of organelles. They also discuss careers in a…
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#51 — Antje Keppler is the Director of Euro-BioImaging Bio-Hub. In this episode of The Microscopists, Antje joins Peter O'Toole to discuss the recent explosion and expansion of techniques in microscopy and how Euro-BioImaging is helping researchers access these. They also chat about fishing in Scandinavia and her reaction after being told girls sho…
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#50 — Michael Sheetz is the Robert A. Welch Distinguished University Chair in Chemistry at the Department of Biochemistry & Molecular Biology at the University of Texas Medical Branch (UTMB) at Galveston. In this episode of the Microscopists, Michael joins Peter O'Toole to tell us about his new exciting work on cell senescence, and his time living …
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#49 — In this episode, we talk to Elisabeth Bik, former microbiome researcher turned scientific integrity consultant. Elisabeth spends her time searching biomedical literature for inappropriately manipulated photographic images and plagiarized text, and often discusses these on Twitter at @MicrobiomDigest. Following her successful scientific career…
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#48 — In this episode, we talk to David Piston, Professor and Head of Cell Biology and Physiology at the Washington University School of Medicine in St Louis. David's first love was physics—until he was made to take a quantum mechanics class in graduate school! He now has a super successful career in biology, using innovative imaging and biochemica…
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#47 — From an early start in the lab at just 14 years old, to running one of the largest neuroscience groups in the world, Ed Boyden is a Professor and group leader in the Departments of Brain and Cognitive Sciences at MIT, and an HHMI investigator. In this episode, we hear all about how despite his recent awards and huge success, he initially stru…
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#46 — Stefan Terjung is operational manager at the Advanced Light Microscopy Facility in Heidelberg, one of the first microscopy core facilities established at the EMBL. We discuss new microscopy techniques, his favourite school subjects and guilty TV pleasures. We also chat about the excellent networking opportunities conferences can provide, fun …
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#45 — Eija Jokitalo is the Director of the Electron Microscopy Unit at the University of Helsinki, whose work focuses on understanding organelle structure during cell division. We chat about why she believes imaging is key to solving biological problems, alternative career pathways inside a core facility and her outreach work in schools. We also he…
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#44 — Gail McConnell, Professor of Biophotonics at the University of Strathclyde chats to Peter O'Toole about her groundbreaking work developing new imaging techniques on the Mesolens, discusses her career highlights, and remembers the time she once got into trouble at an international conference. We'll discuss creating good work-life balance, and …
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#43 — Elizabeth Villa, a Howard Hughes Medical Institute investigator at UC San Diego talks to Peter O'Toole about the benefits of collaborative projects, the advantages and disadvantages of new microscopy techniques, and establishing fun lab traditions. We'll chat about her early career as a Fulbright Scholar, her movement into biology to work wit…
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#42 — Claire Brown, Associate Professor & Director of the Advanced BioImaging Facility at McGill University, talks to Peter O'Toole about the importance of taking care of your staff, how she successfully set up a lab as a single mom and why simpler techniques are often the better choice. We'll also discover why she got involved with Global BioImagi…
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#41 — Ralf Jungmann, Professor and group leader at the Max Planck Institute of Biochemistry and LMU Munich joins Peter O'Toole in this episode of The Microscopists to discuss the most frightening time in his career, how moving back to Germany from the US was the biggest culture shock and why writing grants is so important. Ralf also shares how 80s …
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#40 — Brad Amos, Emeritus Scientist at the MRC Laboratory of Molecular Biology, joins Peter O’Toole in this episode of The Microscopists to discuss his varied career, from zoologist to confocal microscope designer to amateur artist. We’ll discover how Brad developed the confocal microscope taken up by Bio-Rad, as well as the Mesolens microscope, wh…
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#39 — Ever wondered just what it’s like working at the HHMI Janelia Research Campus? Teng-Leong Chew, Director of the Advanced Imaging Center at Janelia, joins Peter O’Toole for episode #39 of The Microscopists to let us know. We’ll also discover what it was like moving from Malaysia to Wisconsin during a blizzard-enforced University of Wisconsin s…
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#38 — W. E. Moerner of Stanford University is a pioneer in the field of super-resolution imaging for cell biology. Tune in as W. E. joins Peter O’Toole and discover more about the work that led to W. E. sharing the 2014 Nobel Prize in Chemistry. We’ll hear why interdisciplinarity is so important in science, why W. E. has had to overcome his tendenc…
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#37 — Peter O’Toole’s guest for episode #37 of The Microscopists is Holly L. Aaron, Director of the CRL Molecular Imaging Center at the University of California Berkeley. Tune in to this candid episode and discover more about Holly’s aversion to grant writing, her plans for her self-built dream home on Hawaii, and why there’s nothing quite like the…
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#36 — Today's guest on The Microscopists is Nobel Laureate Sir Paul Nurse, Chief Executive and Director of The Francis Crick Institute in London. Paul's early career used microscopic screening to identify temperature-sensitive cell-cycle mutants in fission yeast. This work led to the identification of the cell division cycle 2 gene (cdc2), which en…
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#35 — You’re in for a treat in this episode of The Microscopists as we’re joined by Sir Jeremy Farrar, Director of Wellcome. We learn more about Jeremy’s work as an infectious diseases specialist, his rugby- and cricket-playing pedigree, being a member of SAGE during COVID, and unusual wallpapers. In this inspiring episode, Jeremy also reveals his …
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#34 — Michelle S. Itano is the Director of the Neuroscience Center Microscopy Core at the University of North Carolina Chapel Hill. In this episode of The Microscopists, cellular biophysicist Michelle tells us about her role as Editor-in-Chief of Biotechniques, the importance of improving staff retention in core facilities, and how being a Chan Zuc…
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#33 — Mark Ellisman, Director of the National Center for Microscopy and Imaging Research (NCMIR) at UCSD, is a leader in the development of 3D light and electron microscopy and its applications for studying cells of the brain and nervous system. In this episode of The Microscopists, we learn more about Mark’s early passion for taking things apart a…
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#32 — Today’s guest on The Microscopists is none other than Martin Chalfie of Columbia University. In this inspiring episode, we discover more about the work on the discovery and development of GFP that led to Martin sharing the 2008 Nobel Prize in Chemistry. We’ll also hear about some of the early challenges that Martin faced in his career, why he…
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#31 — Joerg Bewersdorf is a leader in developing fluorescence microscopy techniques for biomedical research, such as Pan-Expansion microscopy. In today’s entertaining episode of The Microscopists, we chat to Joerg about his early dreams of space, training as a physicist, straight talking, the (very important) hierarchy of deserts, and making a micr…
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#30 — Prisca Liberali of the Friedrich Miescher Institute for Biomedical Research (FMI) is a pioneer in the field of cellular self-organization and collective behaviors during developmental and regenerative processes. In today’s energetic and inspiring episode of The Microscopists, Peter O’Toole learns more about Prisca’s training as a chemist, her…
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#29 — On this week’s episode of The Microscopists, we chat to Jan Ellenberg, Head of Cell Biology & Biophysics Unit at EMBL, Heidelberg. Jan’s current pioneering work focuses on cell division and nuclear organization, and we learn more about this, as well as how Jan got to grips with the political aspects of his role. We’ll discover more about the …
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#28 — Markus Sauer of the University of Würzburg is a super-resolution microscopist and one of the pioneers behind dSTORM (direct stochastic optical reconstruction microscopy). In the latest episode of The Microscopists, Markus joins Peter O’Toole to discuss his career path, from imaging combustion to imaging single molecules. As we get to know Mar…
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#27 — Judith Klumperman of the University Medical Center (UMC) Utrecht is one of the leaders in the field of electron microscopy and her work has contributed hugely to our understanding of diseases of the endo-lysosomal system. In this episode of The Microscopists, Judith chats to Peter O’Toole about the importance of scientific collaboration, why …
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#26 — You may know Elizabeth M. C. Hillman (Columbia University) as the pioneer behind SCAPE microscopy, but in episode #26 of The Microscopists, we’ll learn more about her early inspirations, how she positions herself between the fields of physics, engineering, and medicine, and how it was while in hospital with a gymnastics injury that she decide…
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#25 — Harald Hess is a pioneer in the fields of high-throughput electron microscopy and super-resolution 3D microscopy, and today we’ll discover more about what inspired him, his move from academia to industry and back again, and who comes off best in his tennis matches with Eric Betzig. We’ll hear how Harald and Eric built the first super-resoluti…
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#24 — In this episode of The Microscopists, we’re joined by astronomer Professor Chris Lintott of the University of Oxford, co-founder of The Zooniverse citizen science platform, and a presenter on the BBC’s The Sky at Night programme. In this wide-ranging and enlightening chat, we discuss early inspirations, the importance of public engagement in …
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#23 — In this episode of The Microscopists, we have a double-header for you as we’re joined by Mark Bray of Novartis and Pearl Ryder of the Carpenter Lab at the Broad Institute. Mark and Pearl share their career histories, from high school to med school to the lab. We take in their career highlights—including Pearl’s founding of the Future PI Slack…
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