최고 Malaria 팟캐스트 (2024)

1
EXTENDED: How AI Chatbots Could Help Predict Antimalarial Drug Resistance Before It Strikes (with Robert Opoka and Elizabeth Winzeler) 12:31

10d ago12:31

12:31

We focus on drug resistance and the troubling news that the frontline drug against malaria, artemisinin, is failing due to resistant parasites in severe cases of malaria, and how the collective efforts of drug development – and the data produced – could be used to build an AI chatbot capable of predicting resistance before it strikes. With Robert O…

1
How to Predict (And Avert) Antimalarial Drug Resistance 1:16

17d ago1:16

1:16

Researchers search for ways to predict antimalarial drug resistance and identify more effective drug combinations. Transcript The front-line treatment for malaria is typically a combination of drugs called artemisinin-based combination therapy. Resistance to treatment has already been reported in mild cases of malaria, but now, for the first time, …

1
‘Big Push’ Needed to Turn Tide on Malaria – WHO 1:23

19d ago1:23

1:23

The World Health Organization has today released its annual World Malaria Report. Here are the takeaways. Transcript The World Health Organization has today released its annual World Malaria Report. Here are the takeaways. Since the turn of the century, the global malaria community has averted over 2.2 billion malaria cases and 12.7 million deaths,…

1
EXTENDED: Listening to Malaria – How Lasers and Ultrasound Could Revolutionize Diagnosis (with Sunil Parikh, Vladimir Zharov and Yap Boum) 11:43

1M ago11:43

11:43

An innovative, non-invasive diagnostic tool that could revolutionize malaria testing, with the potential to be built into wearable devices. In this extended episode of the Johns Hopkins Malaria Minute, we ask: What are the limitations of current malaria diagnostic methods? How is a 'cytophone' - and what makes it innovative? Why is the detection of…

1
The Skin-Contact Malaria Test That Could Revolutionize Diagnostics 1:10

2M ago1:10

1:10

Using lasers and ultrasound, the ‘cytophone’ detects a key byproduct of all malaria parasites. Transcript Among the most commonly used malaria diagnostic tests is the rapid diagnostic test (RDT), which detects malaria antigens from a drop of blood. Whilst RDTs are small and cheap, they're invasive and new strains of the parasite have evolved that c…

1
#12 Where Is Hope? 7:00

2M ago7:00

7:00

There are many reasons to lose hope. But you can choose to remain hopeful. Here are my reasons.저자 Silas Majambere

1
EXTENDED: First Reference Genome Sequence of P. vivax from Ethiopia (with Jane Carlton, Delenasaw Yewhalaw, and Francisco Callejas Hernandez) 8:59

2M ago8:59

8:59

Today, how DNA from a single patient in Ethiopia can shed light on the big picture of malaria. Why is Plasmodium vivax significant in malaria research, especially in Ethiopia? How does genomic sequencing contribute to understanding and controlling malaria? How are advances in sequencing technology influencing malaria research? With Jane Carlton, De…

1
How Comparative Genomics Can Help Find the Best Treatments for Malaria 1:13

3M ago1:13

1:13

'Comparative genomics' helps identify genes that can serve as targets for future drugs and vaccines. Transcript Not all parasites are alike. Genetic mutations mean that malaria parasites evolve differently in different regions – and even within the same region. One species thought to be particularly genetically diverse is Plasmodium vivax. It’s the…

1
EXTENDED: The Surprising Advantage of Transmission-Blocking Vaccines (with Ilinca Ciubotariu, Qixin He and Giovanna Carpi) 9:22

3M ago9:22

9:22

The World Health Organisation has recommended two licenced malaria vaccines. Those vaccines have been a long time coming - but are they the best? In this extended episode of the Johns Hopkins Malaria Minute, we ask: Why is developing a malaria vaccine so challenging? How does antigen variation play affect the effectiveness of malaria vaccines? What…

1
Transmission-Blocking Antigens Show Low Variation, Making Them a Reliable Vaccine Target Across Countries 1:14

3M ago1:14

1:14

A key challenge in developing a malaria vaccine is choosing which stage to target. Transcript A key challenge in developing a malaria vaccine is choosing which stage of the infection to target. You can target the parasite when it enters the body, multiplies in the liver and the blood, or is in the sexual stage, preparing to be picked up by a mosqui…

1
EXTENDED: World Mosquito Day - Gene Drives and CRISPR Technology 13:19

4M ago13:19

13:19

We share a special episode of our podcast to mark World Mosqutio Day. World Mosquito Day, observed annually on August 20th, commemorates British doctor Sir Ronald Ross's discovery in 1897 that female Anopheles mosquitoes transmit malaria to humans. More than a century later, major advancements like genetically modifying mosquitoes—AKA gene drives—h…

1
Gene Drives: A Sharper Tool for the Malaria Toolkit? 1:15

5M ago1:15

1:15

People often talk about the 'malaria toolkit' - how might gene drives fit? Transcript When people talk about malaria, they often mention the 'malaria toolkit' – a set of tools, like bed nets and indoor residual spraying, that are available to help curb the spread of disease. In the past, these tools were trusty go-to's – thanks to their efficacy, s…

1
EXTENDED: CRISPR and Consent (Gene Drives Part I - with Anthony James and John Connolly) 12:24

5M ago12:24

12:24

Gene drives are a novel way of genetically editing the mosquitoes that transmit malaria. They have the potential to dramatically reduce cases and deaths. But the technology they’re based on is new and requires new thinking on regulation. In this first episode of our two-part focus on gene drives, we ask how drives work – examining the CRISPR techno…

1
How Can We Tell Gene Drives Work? 1:19

6M ago1:19

1:19

Gene drives are a promising tool for malaria control - how can we tell they actually work? Transcript Gene drives are a promising new tool for malaria control. They involve releasing genetically modified mosquitoes into the wild – mosquitoes engineered to halt the parasites from developing inside the insects, or that cause the mosquitoes to die. Th…

1
EXTENDED: How Climate Change Could Lead To Faster, More Intense Malaria Transmission (with Alex Eapen) 7:07

6M ago7:07

7:07

Temperature, rainfall, and humidity determine malaria transmission - but climate change is altering each one of those variables. What might this mean for cases of the disease? With Alex Eapen, from the ICMR (Indian Council of Medical Research) in Chennai, India. About The Podcast The Johns Hopkins Malaria Minute is produced by the Johns Hopkins Mal…

1
Increase in Temperature Associated With Decrease in Incubation Period 1:21

6M ago1:21

1:21

Researchers compare the temperature of mosquito breeding spots with a decade early to examine its impact on malaria transmission. Transcript The effects of climate change on malaria are becoming clearer. Anopheles stephensi – an urban form of the malaria mosquito – is changing its geography, moving from Southeast Asia to parts of Africa and India. …

1
EXTENDED: Investigating PfHDAC1 – The Essential Malaria Protein Behind Human Sickness (with Abhishek Kanyal and Krishanpal Karmodiya) 11:04

7M ago11:04

11:04

A single protein helps malaria parasites develop in the blood and cause disease symptoms. Could inhibiting this essential protein help curb the spread of disease? With Abhishek Kanyal and Krishanpal Karmodiya. About The Podcast The Johns Hopkins Malaria Minute is produced by the Johns Hopkins Malaria Research Institute to highlight impactful malari…

1
Blood-Stage Protein Identified as Key Target for Antimalarial Drugs 1:16

7M ago1:16

1:16

A poorly studied malaria protein could serve as a key drug target to help combat the growing problem of resistance. Transcript A poorly studied malaria protein – Plasmodium falciparum histone deacetylase 1 – could serve as a key drug target to help combat the growing problem of resistance. The protein helps regulate the ‘intraerythrocytic’ stage of…

1
#11 A conversation with Dr Fitsum Tadesse, Lead Scientist at AHRI in Ethiopia 59:57

8M ago59:57

59:57

Dr Fitsum Tadesse is a Lead Scientist at the Armauer Hansen Research Institute (AHRI) in Ethiopia, a Wellcome Trust Fellow at LSHTM and an Alan J. Magill Fellow at ASTMH His work mainly focuses on the transmission of malaria parasites from humans to mosquitoes. His group recently demonstrated the contribution of the invasive mosquito, Anopheles ste…

1
EXTENDED: What Sickle Cell Disease Reveals About Malaria and Human Evolution 8:32

8M ago8:32

8:32

How sickle cell disease can be a blessing and a curse. And why we need equity in genomic research and to diversify the genomes we sequence. With Ambroise Wonkam (Johns Hopkins University). About The Podcast The Johns Hopkins Malaria Minute is produced by the Johns Hopkins Malaria Research Institute to highlight impactful malaria research and to sha…

1
The Malaria Legacy of Sickle Cell Disease 1:18

9M ago1:18

1:18

Malaria is one of humanity’s oldest diseases – and one with which we have evolved. Transcript Malaria is one of humanity’s oldest diseases – and one with which we have evolved. Over time, it’s put selective pressure on our genome to respond better to its infection. Sickle cell disease is one example. It causes a defect in hemoglobin – transforming …

1
#10 A Conversation with Dr Anne Gasasira, Senior Programme Officer at the African Leaders Malaria Alliance 1:09:05

9M ago1:09:05

1:09:05

Dr Anne Gasasira is a Ugandan trained medical doctor and epidemiologist. She started her career in malaria and HIV research in the early 2000s. She worked on a research collaboration between Makerere University- University of California San Francisco on antimalarial drug efficacy and HIV–Malaria interaction studies. Since 2015, has been working wit…

1
EXTENDED: From Lab to Legislature – Meet the Scientists Taking on Capitol Hill in the Fight Against Malaria 12:04

9M ago12:04

12:04

On the steps of Capitol Hill, we meet the scientists bringing their scientific battle against malaria into the world of political advocacy. They join a 100+ group of advocates lobbying their members of Congress to fund critical interventions against malaria – becoming ‘malaria champions’ as well. We ask: Why have they decided to join the world of p…

1
Advocacy on Capitol Hill: Uniting Scientific Research and Policy in the Fight Against Malaria 1:17

10M ago1:17

1:17

Malaria champions from 43 states gather in Washington D.C. to lobby their members of Congress about malaria. Transcript The malaria community is diverse. Some work on the parasites, others the mosquito. Others still focus on public health. The battle is being waged on the bench and the field. But there's another community fighting the disease on a …

1
EXTENDED: Odisha's Innovative Approach to Controlling Malaria in Hard-to-Reach Villages (with Praveen Sahu and Jane Carlton) 7:56

10M ago7:56

7:56

Until recently, health workers were the only means to prevent and treat malaria in Odisha, India. In 2017, the state government tried a new strategy: pooling health resources into regional ‘malaria camps’. In this podcast, we ask: What is the current state of malaria in Odisha, India? What challenges does Odisha face in malaria control, especially …

1
‘Malaria Camps’ to Control Malaria in Remote Parts of India 1:42

11M ago1:42

1:42

Malaria in India has fallen in recent decades — but the risk is still high among hard-to-reach communities. A new study has evaluated the system of ‘malaria camps’ — in which health workers provide targeted interventions before the monsoon. Transcript Malaria in India has diminished in past decades — yet the risk is still high among hard-to-reach c…

1
EXTENDED: Behind the Scenes with a Documentary Crew Following the Malaria Vaccine from Trial to Approval (with Catherine Gale and Bill Moss) 12:38

11M ago12:38

12:38

A new documentary tells a story of global scientific collaboration in the development of a new malaria vaccine, R21. Today, we take you behind the scenes with director and producer, Catherine Gale. In this podcast, we ask: Why are malaria vaccines gaining so much attention now? What was the serendipidous origin of the documentary? What are the key …

1
#9. A conversation with Carl Manlan, an Economist working at the intersection of public, private and civil society sectors 59:59

11M ago59:59

59:59

Carl Manlan is an Economist working at the intersection of public, private and civil society sectors. He is a development practitioner with experience in health financing, private foundations, inclusive impact and sustainability.저자 Silas Majambere

1
Documentary Reveals Story of Malaria Vaccine's Creation 0:59

12M ago0:59

0:59

A new documentary from NOVA shines a light on the creation of R21, a new malaria vaccine. Transcript This month, a new documentary from NOVA shines a light on the creation of a new malaria vaccine. ‘The Battle to Beat Malaria’ tells the story of the development of R21 – from creation to WHO approval. Taking you behind the scenes in Oxford, UK, wher…

1
#8. A conversation with Sherwin Charles, CEO of Goodbye Malaria 1:03:40

1y ago1:03:40

1:03:40

Sherwin Charles is a co-founder and the Chief Executive Officer of Goodbye Malaria, an African initiative to eliminate malaria in Southern Africa. In this episode we discuss his journey into the fight against malaria, the role of the private sector and the financing of malaria elimination; the current reliance on commodities and the role of communi…

1
EXTENDED: Rising Temperatures and Extreme Weather Events - The Impact of Climate Change on Malaria (With Martin Edlund and Courtney Murdock) 9:41

1y ago9:41

9:41

As COP28 emphasises the human cost of climate change, what will be the impact of rising temperatures and extreme weather events on malaria transmission? In this podcast, we ask: How was health represented this year at COP? What is the impact of rising temperatures on malaria? How will extreme weather events, like flooding, affect malaria prevalence…

1
Climate Change Threatens Malaria Progress – WHO Report 1:25

1y ago1:25

1:25

The WHO launches its annual World Malaria Report at COP28, the UN's Climate Change Conference. Transcript The World Health Organization (WHO) has released its World Malaria Report for 2023 at the start of COP28, the UN’s Climate Change Conference. The headline figures are concerning. The WHO estimates that there were 249 million cases of malaria la…

1
#7. A conversation with Dr Michael Charles, CEO of RBM Partnership To End Malaria 51:20

1y ago51:20

51:20

Dr Michael Adenkule Charles is the CEO of the RBM Partnership to End Malaria. He is at the forefront of convening and collaborating with over 500 partners, in the combined mission towards the elimination of malaria. In this episode, I chat with Dr Charles about the issues of localization and agenda setting for malaria elimination in Africa; the ove…

1
EXTENDED: The ‘Chemical Vaccine’ for Long-Lasting Malaria Prevention (with Theresa Shapiro) 8:40

1y ago8:40

8:40

An old malaria drug gets a new formulation. But how good is it – and will it drive resistance? In this podcast, we ask: What are the limitations of current malaria vaccines? What is the concept of long-acting injectable (LAI) drugs? What are the clinical and chemical properties of atovaquone that make it suitable for this purpose? With Theresa Shap…

1
Turning Drugs Into Vaccines to Offer Longer-Term Protection Against Malaria 1:08

1y ago1:08

1:08

How ‘chemical vaccines’ could offer long-term protection against malaria in endemic areas, and combat the problems of dosing and drug resistance. Transcript Drugs used to prevent and treat malaria are vital tools in the malaria toolkit – but they aren’t perfect. When used to prevent malaria, people must remember to take them regularly, or they won’…

1
EXTENDED: How Blood Spots are Mapping Artemisinin Resistance (with Didier Ménard) 7:06

1y ago7:06

7:06

Drug efficacy studies are revealing the spatial distribution of mutations causing artemisinin resistance - and it all starts with a drop of blood. In this podcast, we ask: What is artemisinin resistance? What are some of the key molecular markers underpinning it? How can we overcome it? With Didier Ménard, Director of the Institute of Parasitology …

1
#6. My take on the 9th PAMCA annual conference 11:32

1y ago11:32

11:32

In this monologue, I will talk about five positive things I saw during the 9th annual conference of the Pan-African Mosquito Control Association, and four things I have questions about.저자 Silas Majambere

1
Is Artemisinin Drug Resistance in Africa on the Rise? 1:08

1y ago1:08

1:08

Researchers examine the rise of artemisinin drug resistance in Eritrea - and search for its genetic basis. Transcript Artemisinin – a key antimalarial drug – and other drugs derived from it, are fast losing their effectiveness across South East Asia and increasingly in Africa, too. To investigate this, researchers conducted a review of drug efficac…

1
Mentoring in Medicine - Making It Matter

1y ago

—

Mentors are instrumental in the professional and personal growth of healthcare professionals. However, mentoring relationships often fail to realize their full potential. Attendees will be encouraged and equipped to initiate mentoring relationships that provide both mentor and mentee with a rewarding experience.…

1
EXTENDED: What Genomics Can Reveal about Malaria’s Recent US Appearance (with Jane Carlton) 8:31

1+ y ago8:31

8:31

In 1951, malaria was eliminated from the US. But just this past summer, the parasite that causes the disease has re-infected local mosquitoes and caused a handful of cases of malaria in three US states. In this interview podcast, we ask: What should we make of these cases? Is the public possibly at risk of this once-eliminated disease? How can geno…

1
Malaria Is Making a Comeback to the US. Why? 1:17

1+ y ago1:17

1:17

Malaria returns to the US for the first time in decades. We share what we know so far. Transcript Today, another reminder that infectious diseases respect no borders. Malaria, a disease that was once endemic globally, has returned to the US for the first time in two decades. A number of cases have been confirmed in Florida, Texas and, most recently…

1
#5. A conversation with Founder and CEO of Speak Up Africa, Yacine Djibo - Part 2 37:56

1+ y ago37:56

37:56

Yacine Djibo founded Speak Up Africa in 2011 to discover and implement effective, sustainable solutions to the most challenging problems facing the African people. Focusing on strategic communications, policy and advocacy, Speak Up Africa is dedicated to collaborating with African leaders and citizens to take on issues such as malaria, neglected tr…

1
Responding to Gods Command and Commission

1+ y ago

—

In this session, It will seek to help guide you on how to respond to God’s Command and Commission, The quest for discovering and following God’s will and purpose for one’s life is often an illusion to many children of the Living God, Many believers resorts to imitating others and or live a hypocritical phantom life as they are tied down to daily en…

1
EXTENDED: How Scientific Collaboration Across Three Continents Turned a Problem Into a Solution 12:36

1+ y ago12:36

12:36

In 2013, on the outskirts of Madrid, GSK was gearing up to test new medicines against malaria. But they had a problem. In this month's podcast, we're joined by Janneth Rodrigues from GSK, Marcelo Jacobs-Lorena from Johns Hopkins University, and Etienne Bilgo from IRSS to share a story of collaboration that spans three continents, and which turned a…

1
"The Talk about . . . fundraising and MedSend's solution"

1+ y ago

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Are you comfortable asking people for money? Do you understand the critical areas you must address if you are going to ask people to invest in you? This session will give you an understanding of the basics in fundraising that is fundamental to anyone in ministry. You will learn 5 critical things you must do in order to raise your own support. There…

1
#4. A conversation with Founder and CEO of Speak Up Africa, Yacine Djibo - Part 1 38:56

1+ y ago38:56

38:56

Yacine Djibo founded Speak Up Africa in 2011 to discover and implement effective, sustainable solutions to the most challenging problems facing the African people. Focusing on strategic communications, policy and advocacy, Speak Up Africa is dedicated to collaborating with African leaders and citizens to take on issues such as malaria, neglected tr…

1
A Naturally Occurring Bacterium Inhibits Malaria Parasites in the Mosquito 1:22

1+ y ago1:22

1:22

A naturally occurring bacterium renders the mosquito a poor transmitter of the malaria parasite. Transcript Scientists often grow mosquitos in the laboratory and infect them with malaria parasites to test new drugs and explore vector control. Unexpectedly, in a lab run by GSK in Spain, mosquitoes gradually lost the ability to sustain parasite devel…

1
Biomedical Research and Faith-Based Healthcare

1+ y ago

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This session will consider case studies of biomedical research in mission contexts, derive best practices in biomedical research that enhance the work of mission institutions, and describe how to get involved in biomedical research in faith-based settings. Presentation Slides: https://bit.ly/gmhc2022_marktopazian_biomedicalresearchandfaith…

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#3. A conversation with Anthropologist Ann Kelly - Part2 41:36

1+ y ago41:36

41:36

In this episode we pick up from where we left in part 1 and discuss the issues of agenda setting, the moral imperatives around malaria control… We end this episode discussing human dignity and the reasons for remaining hopeful in this world despite all the challenges we face.저자 Silas Majambere

1
EXTENDED: Will the Malaria Vaccine Mean a World Free From the Disease? (With Pauline Formaglio and William Moss) 10:02

1+ y ago10:02

10:02

After decades of research, the world’s first malaria vaccine is finally being rolled out in Africa. It’s a landmark in malaria success – but will it deliver a public health victory? In this podcast, we reveal the elusive target of the malaria vaccine and unpack the complex story of its development.

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