최고 Drug Discovery 팟캐스트 (2025)

1
Eliminating an Invisible Threat 13:48

2y ago13:48

13:48

Lurking among cell culture facilities across academia and the biopharmaceutical industry is an invisible threat. Microscopic organisms, no more than 2-3 micrometers in length and approximately 25 times smaller than a spec of dust floating in the air or hiding behind your couch, may creep into cell culture dishes, infiltrate cells, and propagate, ca…

1
Behind the Scenes: Manufacturing Viruses for Hemophilia Gene Therapy 15:38

2+ y ago15:38

15:38

Gene therapy promises the possibility of replacing damaged and faulty disease-causing genes with functional copies, essentially rescuing disease-causing phenotypes and restoring individuals to health. At the heart of this technology are viral vectors, little vessels that leverage the evolutionary power of viruses to penetrate and shuttle genetic in…

1
Uncovering Discoveries Hidden in the Freezer 11:45

3y ago11:45

11:45

In an increasingly digital world, many scientists still work with basic paper and pen. Often, critical information gathered during clinical trials gets buried in laboratory notebooks or overly complex excel documents. Unearthing this information and creating a central hub for big scientific data is more than simply a technical advancement; it is cr…

1
Nick Lynch of the Pistoia Alliance on AI as a Strategic Focus 32:08

6+ y ago32:08

32:08

On this episode, I speak with Nick Lynch of the Pistoia Alliance ( www.pistoiaalliance.org ), a global nonprofit community of life science stakeholders that works to lower barriers to R&D innovation. A new area of strategic focus is artificial intelligence, which Nick oversees. On this episode, you'll learn challenges with AI that the Pistoia Allia…

1
Lucas Siow of ProteinQure on AI for Protein-Based Drugs 33:56

6+ y ago33:56

33:56

On this episode, I speak with Lucas Siow, Head of Business Operations at ProteinQure ( www.proteinqure.com ). ProteinQure uses artificial intelligence and quantum computing to design protein-based drugs such as antibodies and peptides. On this episode, you'll learn the benefits of protein-based drugs, challenges with discovering them, and how Prote…

1
Regina Barzilay, AI Small Molecule Discovery and Synthesis 28:56

6+ y ago28:56

28:56

On this episode, I speak with Regina Barzilay of MIT's Machine Learning for Pharmaceutical Discovery and Synthesis consortium ( http://mlpds.mit.edu ). Regina is a prolific researcher with many highly cited papers in machine learning. On this episode, you'll learn what drove the need for the consortium, the importance of standards and benchmarks fo…

1
Tim Guilliams and David Brown, Healx, AI for Rare Diseases 37:34

6+ y ago37:34

37:34

On this episode, I speak with Tim Guilliams and David Brown of Healx. Healx uses AI to repurpose existing drugs for rare diseases. They claim their approach can bring new treatments to patients 80% faster and 90% cheaper. On this episode, you’ll learn how rare diseases are surprisingly common, why drug repurposing holds promise to treat them, and h…

1
John Cassidy, CEO, Cambridge Cancer Genomics, AI in Oncology 24:03

6+ y ago24:03

24:03

On this episode, I speak with John Cassidy, CEO of Cambridge Cancer Genomics ( www.ccg.ai ). CCG aims to transform oncology by combining liquid biopsy with genomics and artificial intelligence to predict disease progression and improve treatment. On this episode, you’ll learn about the challenges with chemotherapy that CCG is tackling, the role tha…

1
Kristen Fortney, CEO of BioAge Labs, on AI Aging Research 25:31

6+ y ago25:31

25:31

On this episode, I speak with Kristen Fortney, founder and CEO of BioAge Labs ( www.bioagelabs.com ). Kristen leads one of just a few companies focused explicitly on aging itself, rather than the diseases for which aging puts people at greater risk. In this episode, you’ll learn how BioAge combines unique data sources with in silico analysis and la…

1
Sam Cooper, CEO of Phenomic AI, on Automated HCS and More 23:35

6+ y ago23:35

23:35

On this episode, I speak with Sam Cooper, cofounder and CEO of Phenomic AI ( www.phenomic.ai ). Sam and his team use machine learning for automated image analysis to study cell biology and screen drugs. But that’s just the beginning. In this episode, you’ll learn about Phenomic’s distinct approach to drug discovery, its use of machine learning for …

1
Shai Shen-Orr, Chief Scientist, CytoReason, AI in Immunology 31:37

6+ y ago31:37

31:37

On this episode, I speak with Shai Shen-Orr, cofounder and chief scientist of CytoReason ( www.cytoreason.com ). CytoReason has created a machine learning model of the immune system. This model can integrate data from multiple sources to support drug discovery, the creation of diagnostic tools, and more. In this episode, you’ll learn about systems …

1
Leila Pirhaji, CEO of ReviveMed, on AI for Metabolomics 28:33

6+ y ago28:33

28:33

On this episode, I speak with Leila Pirhaji, founder and CEO of ReviveMed ( www.revive-med.com ). ReviveMed uses artificial intelligence to unlock the therapeutic potential of metabolomics. Before learning about ReviveMed, I knew little about metabolomics. Leila is an articulate and enthusiastic teacher, and her passion is infectious. In this episo…

1
Mostapha Benhenda of Startcrowd on AI Drug Discovery Hype 20:21

7y ago20:21

20:21

On this episode, I speak with Mostapha Benhenda of Startcrowd ( http://www.startcrowd.club ). In January, Mostapha wrote a controversial article critiquing several research labs ( https://bit.ly/2qINvQ9 ). Some accused him of using the article just to promote his service. Others agreed with his criticisms. A few took steps to address them. I caught…

1
Mauro Cozzi, Researchably, AI for Better Biomedical Search 29:58

7y ago29:58

29:58

On this episode, I speak with Mauro Cozzi, co-founder of Researchably ( www.researchably.com ). Researchably is a biomedical search engine that uses artificial intelligence to save researchers time—Mauro says up to 90%—searching for scientific papers. I spoke with Mauro about how Researchably got started, how it helps researchers find relevant lite…

1
Dekel Gelbman, CEO of FDNA, on "Next-Generation Phenotyping" 30:36

7y ago30:36

30:36

For the inaugural episode of Artificial Intelligence in Drug Discovery, I spoke with Dekel Gelbman, CEO of FDNA ( https://www.fdna.com/ ). FDNA enables precision medicine by using artificial intelligence for next-generation phenotyping. Their technology links genetic traits with phenotypic characteristics such as facial structure. Listen now to lea…