#220 ‒ Ketamine: Benefits, risks, and promising therapeutic potential | Celia Morgan, Ph.D.

1:27:36
 
공유
 

Manage episode 339297305 series 2352826
Player FM과 저희 커뮤니티의 Peter Attia, MD, Peter Attia, and MD 콘텐츠는 모두 원 저작자에게 속하며 Player FM이 아닌 작가가 저작권을 갖습니다. 오디오는 해당 서버에서 직접 스트리밍 됩니다. 구독 버튼을 눌러 Player FM에서 업데이트 현황을 확인하세요. 혹은 다른 팟캐스트 앱에서 URL을 불러오세요.

View the Show Notes Page for This Episode

Become a Member to Receive Exclusive Content

Sign Up to Receive Peter’s Weekly Newsletter

Celia Morgan is a Professor of Psychopharmacology at the University of Exeter who has authored numerous publications on the potential therapeutic uses of ketamine in mental healthcare. In this episode, Celia dives deep into the neurobiology of ketamine, how it affects users, and how it differs from other, more classical psychedelics (LSD, MDMA, PCP, and psilocybin). She explains the potential promise of ketamine as a treatment for recalcitrant depression and addiction, and she details the results from her clinical trials in these areas. She discusses the importance of using ketamine in combination with psychotherapy to maximize its benefits, the potential risks associated with ketamine use, and advice for those interested in the therapeutic use of ketamine.

We discuss:

  • Celia’s training and interest in ketamine [2:15];
  • The history of ketamine, medical uses, and use as a party drug [3:30];
  • Neurobiology and pharmacology of ketamine [8:15];
  • Ketamine regulation and abuse, and how it compares with psychedelics and other molecules [18:15];
  • Ketamine as a therapeutic for depression [30:45];
  • The brain under the influence of ketamine and theoretical mechanisms for its anti-depressive effects [48:00];
  • Risks and concerns with overusing ketamine, and what an intermittent or maintenance dose might look for a patient [57:15];
  • Treating addiction with ketamine: Celia’s studies of alcohol dependance [1:04:00];
  • Advice for people considering the therapeutic use of ketamine [1:19:45];
  • More.

Connect With Peter on Twitter, Instagram, Facebook and YouTube

282 에피소드