Iran's attack on Israel is a major escalation. What comes next for the region?

Consider This from NPR

Iran launched a barrage of more than 300 drones and missiles at Israel over the weekend, saying it was in response to an airstrike earlier this month that hit Iran's consulate in Syria and killed seven Iranian military officials, including two generals.
Israel neither confirmed nor denied responsibility for the Syria strike, though the Pentagon said Israel was responsible.
Sima Shine is a former senior Israeli intelligence official. She now runs the Iran desk at the Institute for National Security Studies in Tel Aviv. She says this attack is "crossing the Rubicon" from the point of view of Iran, and explains what Israel's retaliation could be.
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