Fabricated images threaten the integrity of Alzheimer’s research (Ep 90)

Big Biology

Art Woods, Cam Ghalambor, and Marty Martin, Art Woods, Cam Ghalambor, and Marty Martin에서 제공하는 콘텐츠입니다. 에피소드, 그래픽, 팟캐스트 설명을 포함한 모든 팟캐스트 콘텐츠는 Art Woods, Cam Ghalambor, and Marty Martin, Art Woods, Cam Ghalambor, and Marty Martin 또는 해당 팟캐스트 플랫폼 파트너가 직접 업로드하고 제공합니다. 누군가가 귀하의 허락 없이 귀하의 저작물을 사용하고 있다고 생각되는 경우 여기에 설명된 절차를 따르실 수 있습니다 https://ko.player.fm/legal.

1+ y ago 1:02:19

MP3•에피소드 홈

What happens when potential fraud is detected in research papers on major medical issues?

In this episode, we talk to Charles Piller, an investigative journalist who published a shocking story in Science magazine in July this year laying out compelling evidence for misconduct in multiple journal articles on Alzheimer’s disease. This misconduct appears to have occurred in recent papers involving the experimental drug, simulfilam, as well as older, foundational papers in Alzheimer’s research.

Charles’s story focuses on the sleuthing of Matthew Schrag, a neuroscientist and physician at Vanderbilt University who studies Alzheimer’s disease himself. In an extensive (even heroic) effort, Schrag identified over 100 potentially manipulated images in multiple major research papers. We talk with Charles about the consequences of those seemingly fraudulent images for the field and for public trust in science. We also talk about the potential consequences for whistleblowers like Schrag, and what journals and funding agencies are doing to support integrity in basic research.

Cover art: Keating Shahmehri

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