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Gut is a leading international journal in gastroenterology and hepatology. It has an established reputation for publishing first class clinical research of the alimentary tract, the liver, biliary tree and pancreas. Gut delivers up-to-date, authoritative, clinically oriented coverage of all areas in gastroenterology. Regular features include articles by leading authorities, reports on the latest treatments for diseases, reviews and commentaries. Subscribers to Gut also receive Frontline Gast ...
 
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show series
 
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, UK, interviews Professor Gisbert from the Gastroenterology Department, University Hospital of La Princesa, Madrid, Spain. The podcast is focused on "European Registry on Helicobacter pylori management (Hp-EuReg): patterns and tren…
 
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, UK, interviews Professor Delzenne, President of the Louvain Drug Research Institute, at the UCLouvain, Brussels, Belgium. The podcast is focused on "Discovery of the gut microbial signature driving the efficacy of prebiotic interv…
 
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital interviews Dr Rima Chakaroun who is a Clinician Scientist, Resident physician at the University Hospital in Leipzig, Germany, specialising in Endocrinology and Metabolic disease and a postdoctoral researcher and clinical investigat…
 
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital interviews Dr Melina Arnold from the Section of Cancer Surveillance, International Agency for Research on Cancer, Lyon, France. The podcast is focussed on "Global burden of oesophageal and gastric cancer by histology and subsite in…
 
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital interviews Professor Silvia Sookoian, who is Head of the Department of Clinical & Molecular Hepatology and Vice-Chair of Institute of Medical Research, at the Institute of Medical Research, Strategic Alliance between the National S…
 
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital interviews Professor Madgy El-Salhy, who is a Professor of Gastroenterology at Bergen University and Consultant Gastroenterologist at Stord Hospital, Norway, on the paper ‘Efficacy of faecal microbiota transplantation for patients …
 
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital interviews Professor Inga Peter, who is a Professor in the Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, on "Infants born to mothers with IBD present with altered gut microbiome that transfe…
 
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital interviews Professor Paul O'Toole; who is Professor of Microbial Genomics, Head of School of Microbiology and Principal Investigator in APC Microbiome Ireland, an SFI funded centre at University College Cork, Ireland, on "Mediterra…
 
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital interviews Professor Jacques Bergman who is Professor of Gastrointestinal Endoscopy at the Amsterdam University Medical Center, Amsterdam on "Endoscopic duodenal mucosal resurfacing for the treatment of type 2 diabetes mellitus: on…
 
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, interviews Dr Cathryn Edwards, BSG President and Consultant Gastroenterologist at Torbay Hospital, Devon and Dr Nick Kennedy, Consultant Gastroenterologist, Royal Devon and Exeter NHS Foundation Trust on the British Society of Gas…
 
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital interviews Ms Rebecca Siegel, Scientific Director of Surveillance Research at the American Cancer Society. Ms Rebecca Siegel is first author on the paper 'Global patterns and trends in colorectal cancer incidence in young adults' p…
 
Dr Christopher Lamb, Clinical Intermediate Fellow at Newcastle University and Honorary Consultant in Gastroenterology at the Newcastle upon Tyne Hospitals NHS Foundation Trust discusses the BSG guidelines on the management of inflammatory bowel disease in adults with Associate Editor of GUT Dr Philip Smith. Read the article: https://gut.bmj.com/con…
 
Evidence-based guidelines on the management of pancreatic cystic neoplasms (PCN) are lacking. The guideline discussed in this podcast is a joint initiative of the European Study Group on Cystic Tumours of the Pancreas, United European Gastroenterology, European Pancreatic Club, European-African Hepato-Pancreato-Biliary Association, European Digesti…
 
Clostridium difficile (C. difficile, C. diff or CDI) is a bacterium associated with the intake of antibiotics which causes diarrhoea. It is easily spread to others, both in hospital and a household environments.C. Diff infections are generally treated with antibiotics. Recurrent infection is successfully treated with faecal microbiota transplantati…
 
Prioritising research and funding could have a significant impact on reducing colorectal cancer disease burden over the next 5 years. The conclusions are included in a study recently published by Gut titled “Critical research gaps and recommendations to inform research prioritisation for more effective prevention and improved outcomes in colorectal…
 
In this episode Mairi McLean, Associate Editor of Gut journal, talks to Matias Avila and Carmen Berasai, University of Navarra, Pamplona, Spain. They discuss their published paper "Fibroblast growth factor 15/19 (FGF15/19) protects from diet-induced hepatic steatosis: development of an FGF19-based chimeric molecule to promote fatty liver regenerati…
 
In this episode Mairi McLean, Associate Editor of Gut journal, talks to Fergus Shanahan, Professor and Chair of the Department of Medicine at University College Cork. They discuss his recent paper in Gut entitled "Feeding the microbiota: transducer of nutrient signals for the host" Full text - http://gut.bmj.com/content/early/2017/06/29/gutjnl-2017…
 
In this episode Mairi McLean, Associate Editor of Gut journal, talks to Benoit Chassaing, Georgia State University - Center for Inflammation, Immunity and Infection, about his recently published paper "Dietary emulsifiers directly alter human microbiota composition and gene expression ex vivo potentiating intestinal inflammation". Full paper>> http…
 
In this episode Mairi McLean, Associate Editor of Gut journal, talks to Giovanni Cammarota and Gianluca Ianiro from the Agostino Gemelli University. They discuss the April editors choice paper "European consensus conference on faecal microbiota transplantation in clinical practice". Full paper >> http://gut.bmj.com/content/early/2017/01/13/gutjnl-2…
 
In this episode Mairi McLean, Education Editor for Gut, talks to Dr Katja Breitkopf-Heinlein, Medical Faculty Mannheim, Heidelberg University, about her recently published paper "BMP-9 interferes with liver regeneration and promotes liver fibrosis". Full paper >> http://gut.bmj.com/content/66/5/939저자 BMJ talk medicine
 
In this podcast Mairi McLean interviews Dr Gianluca Ianiro about the editors choice paper "Antibiotics as deep modulators of gut microbiota: between good and evil." Full paper >> http://gut.bmj.com/content/65/11/1906.full?sid=4929814b-b6f1-43d2-9af1-964357aa664c저자 BMJ talk medicine
 
In this episode Mairi McLean talks to Professor Fock about his recently published paper; "Asia-Pacific consensus on the management of gastro-oesophageal reflux disease: an update focusing on refractory reflux disease and Barrett's oesophagus" Full paper >> http://gut.bmj.com/content/65/9/1402.full?sid=13ba6d1c-8c84-4ae9-9cd3-0bab0fa2b3a9…
 
In this podcast Dr Mairi McLean talks to Dr Sonia Friedman about the May editors choice paper "Live birth and adverse birth outcomes in women with ulcerative colitis and Crohn's disease receiving assisted reproduction: a 20-year nationwide cohort study". Full text > http://gut.bmj.com/content/65/5/767.full…
 
In this podcast Dr Mairi McLean talks to Professor Dirk Haller about his editors choice paper "Dysbiotic gut microbiota causes transmissible Crohn's disease-like ileitis independent of failure in antimicrobial defence." Read the full paper >> http://gut.bmj.com/content/65/2/225.full저자 BMJ talk medicine
 
In this podcast Dr Mairi McLean talks to Dr Joanna Jalanka about her recently published article in Gut entitled "Effects of bowel cleansing on the intestinal microbiota". They discuss what was already known in the field and what has since been discovered, and how long these effects last and how the microbiota were measured.…
 
Mairi McLean talks to Thaddeus S Stappenbeck, Department of Pathology and Immunology, Washington University School of Medicine, about his paper: Development of an enhanced human gastrointestinal epithelial culture system to facilitate patient-based assays. Read the full paper: http://goo.gl/xeWDHz저자 BMJ talk medicine
 
Helicobacter pylori strains that express the a protein that increases the risk of gastric cancer. However, the precise mechanisms through which the cancer risk is heightened have not been fully investigated and understood.In this podcast Dr Mairi McLean talks to Dr Lydia Wroblewski from the Vanderbilt University School of Medicine about the study h…
 
Acute renal failure (ARF) is a common complication in patients with decompensated cirrhosis. The traditional diagnostic criteria of renal failure in these patients were proposed in 1996 and have been refined in subsequent years. More recently the International Club of Ascites (ICA)redefined the criteria to reach a new definition of acute kidney inj…
 
Epigenetic alterations accumulate in normal-appearing tissues of patients with cancer, producing an epigenetic field defect. Cross-sectional studies show that the degree of the defect may be associated with risk in some types of cancer, especially cancers associated with chronic inflammation. Dr Mairi McLean speaks to Dr Toshikazu Ushijima about hi…
 
The genetic basis of inflammatory bowel disease (IBD) is incompletely understood, and the aim of a recent study in Gut was to identify rare genetic variants involved in the pathogenesis of IBD.Mairi McLean speaks to authors Sebastian Zeissig, Department of Internal Medicine I, University Medical Center Schleswig-Holstein, and Andre Franke, Institut…
 
The glands of the stomach body and antral mucosa contain a complex compendium of cell lineages. In lower mammals, the distribution of oxyntic glands and antral glands define the anatomical regions within the stomach. Now a paper in Gut has examined in detail the distribution of the full range of cell lineages within the human stomach. Mairi McLean …
 
The identification of a distinct syndrome, designated eosinophilic oesophagitis (EoE), with its own clinical and histopathological characteristics, was first described in the early 1990s. Meanwhile intense research has uncovered many molecular, immunological and clinical aspects of this chronic-inflammatory disorder. In this podcast, Mairi McLean t…
 
Inflammatory bowel disease is driven by a seemingly aberrant immune response to the gut microbiota with disease development dictated by genetics and environmental factors. A model exemplifying this notion is work by Andrew Gewirtz, Center for Inflammation, Immunity, & Infection, Georgia State University, and colleagues, demonstrating that colonisat…
 
Despite the success of hepatitis B virus vaccination in preventing new infection in endemic areas, chronic hepatitis B still poses a heavy burden globally. There are approximately 350 million carriers in the world, with an estimated 60 000 persons dying annually of hepatitis B-related cirrhosis and hepatocellular carcinoma.In a study recent publish…
 
Mairi McLean talks to Robin Spiller, NIHR Nottingham Digestive Diseases Biomedical Research Unit, and David Tooth, School of Biomedical Sciences, University of Nottingham, about their paper: Characterisation of faecal protease activity in irritable bowel syndrome with diarrhoea: origin and effect of gut transit. Read the full article: http://goo.gl…
 
Mairi McLean talks to Andres Acosta and Barham K Abu Dayyeh, both Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, about their review on the management of obesity. Read the full paper: http://goo.gl/V37xaq저자 BMJ talk medicine
 
Necrotising enterocolitis (NEC) remains one of the primary causes of morbidity and mortality in neonates and alternative strategies are needed. Stem cells have become a therapeutic option for other intestinal diseases, which share some features with NEC. Along with colleagues, Simon Eaton and Paolo De Coppi, both from University College London Inst…
 
Gut's education editor Mairi McLean discusses highlights from the guidelines on the diagnosis and management of Barrett's oesophagus with authors Rebecca Fitzgerald and Massimiliano di Pietro, both from the MRC Cancer Unit, University of Cambridge. Read the full paper here: http://bit.ly/1kkPkVW저자 BMJ talk medicine
 
Mairi McLean talks to Markus Peck-Radosavljevic, Division of Gastroenterology & Hepatology, Medical University Vienna, about his study looking at carvedilol for primary prophylaxis of variceal bleeding in cirrhotic patients with haemodynamic non-response to propranolol. Read the full paper here: bit.ly/1991biw…
 
Mairi McLean talks to Anna Paterson and Rebecca Fitzgerald, both MRC Cancer Cell Unit, Hutchison-MRC Research Centre, Cambridge, about their study investigating whether a receptor tyrosine kinase (RTK) array could be used to select the most effective therapeutic strategies in molecularly heterogeneous oesophago-gastric adenocarcinomas. Read the ful…
 
Fibrosis associated with chronic pancreatitis is an irreversible lesion that can disrupt pancreatic exocrine and endocrine function. Currently, there are no approved treatments for this disease. In this podcast Mairi McLean, Gut education editor, talks to Professor Yoshiro Niitsu from Sapporo Medical University School of Medicine about his manuscri…
 
Mairi McLean talks to Patrick Tan, associate professor, Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School Singapore, and Heike Grabsch, Pathology and Tumour Biology, Leeds Institute of Molecular Medicine, University of Leeds, about their genomic meta-analysis to identify predictors of survival in patients with gastric cancer. See also:…
 
In this podcast, Mairi McLean interviews Julián Panés and Azucena Salas, both from the Department of Gastroenterology, IDIBAPS, Hospital Clínic, CIBER-EHD in Barcelona, Spain. They disuse their recent article, looking at transcription in the intestinal mucosa of patients with ulcerative colitis. read the full article online: http://tinyurl.com/n3uy…
 
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